Results 1 to 10 of about 1,477,984 (353)

TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae

open access: yesBMC Biology, 2021
Background Target of Rapamycin Complex 1 (TORC1) is a highly conserved eukaryotic protein complex that couples the presence of growth factors and nutrients in the environment with cellular proliferation.
Mohammad Alfatah   +10 more
doaj   +1 more source

Applications of transformer-based language models in bioinformatics: a survey

open access: yesBioinformatics Advances, 2023
Summary The transformer-based language models, including vanilla transformer, BERT and GPT-3, have achieved revolutionary breakthroughs in the field of natural language processing (NLP).
Shuang Zhang   +5 more
semanticscholar   +1 more source

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

open access: yesNucleic Acids Res., 2021
The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) represents the 2019 merger of VectorBase with the EuPathDB projects.
Beatrice Amos   +65 more
semanticscholar   +1 more source

A Markov blanket-based method for detecting causal SNPs in GWAS

open access: yesBMC Bioinformatics, 2010
Background Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases.
Han Bing, Park Meeyoung, Chen Xue-wen
doaj   +1 more source

Facilitating bioinformatics reproducibility with QIIME 2 Provenance Replay.

open access: yesPLoS Computational Biology, 2023
Study reproducibility is essential to corroborate, build on, and learn from the results of scientific research but is notoriously challenging in bioinformatics, which often involves large data sets and complex analytic workflows involving many different ...
Christopher R Keefe   +7 more
doaj   +1 more source

Graph Neural Networks and Their Current Applications in Bioinformatics

open access: yesFrontiers in Genetics, 2021
Graph neural networks (GNNs), as a branch of deep learning in non-Euclidean space, perform particularly well in various tasks that process graph structure data.
Xiao-Meng Zhang   +3 more
semanticscholar   +1 more source

MACBenAbim: A Multi-platform Mobile Application for searching keyterms in Computational Biology and Bioinformatics [PDF]

open access: yes, 2012
Computational biology and bioinformatics are gradually gaining grounds in Africa and other developing nations of the world. However, in these countries, some of the challenges of computational biology and bioinformatics education are inadequate ...
Adewumi, A. O.   +2 more
core   +1 more source

Explainable AI for Bioinformatics: Methods, Tools, and Applications [PDF]

open access: yesBriefings Bioinform., 2022
Artificial intelligence (AI) systems utilizing deep neural networks and machine learning (ML) algorithms are widely used for solving critical problems in bioinformatics, biomedical informatics and precision medicine.
Md. Rezaul Karim   +6 more
semanticscholar   +1 more source

Development of Integrative Bioinformatics Applications using Cloud Computing resources and Knowledge Organization Systems (KOS). [PDF]

open access: yes, 2005
Use of semantic web abstractions, in particular of domain neural Knowledge Organization Systems (KOS), to manage distributed, cloud based, integrative bioinformatics infrastructure.
Jonas Almeida   +3 more
core   +2 more sources

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

open access: yesNucleic Acids Research, 2008
Functional analysis of large gene lists, derived in most cases from emerging high-throughput genomic, proteomic and bioinformatics scanning approaches, is still a challenging and daunting task.
Da Wei Huang   +2 more
semanticscholar   +1 more source

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