Results 51 to 60 of about 1,268,351 (323)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Reproducible bioinformatics project: a community for reproducible bioinformatics analysis pipelines
BMC Bioinformatics, 2018 Background Reproducibility of a research is a key element in the modern science and it is mandatory for any industrial application. It represents the ability of replicating an experiment independently by the location and the operator.
Neha Kulkarni +8 more
doaj +1 more source
Flow cytometry bioinformatics. [PDF]
PLoS Computational Biology, 2013 Flow cytometry bioinformatics is the application of bioinformatics to flow cytometry data, which involves storing, retrieving, organizing, and analyzing flow cytometry data using extensive computational resources and tools.
Kieran O'Neill +3 more
doaj +1 more source
Simulated single molecule microscopy with SMeagol
, 2016 SMeagol is a software tool to simulate highly realistic microscopy data based on spatial systems biology models, in order to facilitate development, validation, and optimization of advanced analysis methods for live cell single molecule microscopy data ...
Boucharin, Alexis +4 more
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Structural and energetic basis of marine phytochemicals as dengue NS1 protein inhibitors
Scientific ReportsDengue, spread by Aedes aegypti and Aedes albopictus, causes 390 million infections, 50 million illnesses, and 24,000 fatalities, including over 4.5 million in 2023.
Sanjida Mahjabin Sanju +9 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Bioinformatics and Biology Insights, 2008 The past twenty years have witnessed an explosion of biological data in diverse database formats governed by heterogeneous infrastructures. Not only are semantics (attribute terms) different in meaning across databases, but their organization varies ...
Nadine Schuurman, Agnieszka Leszczynski
doaj +2 more sources
The Genome Solver Project: Faculty Training and Student Performance Gains in Bioinformatics
Journal of Microbiology & Biology Education, 2019 Bioinformatics brings together biology, mathematics, statistics, and computer science to analyze biological sequence information. Anyone with a computer, access to the Internet, and basic training in this field can contribute to genomics research.
Vinayak Mathur +4 more
doaj +1 more source
Bioinformatics: A challenge for statisticians [PDF]
, 2009 Bioinformatics is a subject that requires the skills of biologists, computer scientists, mathematicians and staisticians. This paper introduces the reader to one small aspect of the subject: the study of microarrays. It describes some of the complexities
Upton, Graham J G
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