Results 101 to 110 of about 1,093,449 (328)

Mass spectrometry and bioinformatics analysis data

Data in Brief, 2015
2DE and 2D-DIGE based proteomics analysis of serum from women with endometriosis revealed several proteins to be dysregulated. A complete list of these proteins along with their mass spectrometry data and subsequent bioinformatics analysis are presented here. The data is related to "Investigation of serum proteome alterations in human endometriosis" by
Mainak Dutta, Elavarasan Subramani, Khushman Taunk, Akshada Gajbhiye, Shubhendu Seal, Namita Pendharkar, Snigdha Dhali, Chaitali Datta Ray, Indrani Lodh, Baidyanath Chakravarty, Swagata Dasgupta, Srikanth Rapole, Koel Chaudhury   +12 more
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Construction and Analysis of a ceRNA Network Reveals Potential Prognostic Markers in Colorectal Cancer

Frontiers in Genetics, 2020
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide and is derived from an accumulation of genetic and epigenetic changes.
Li Guo, Guowei Yang, Yihao Kang, Sunjing Li, Rui Duan, Lulu Shen, Wenwen Jiang, Bowen Qian, Zibo Yin, Tingming Liang, Tingming Liang   +10 more
doaj   +1 more source

Data Analysis and Bioinformatics [PDF]

, 2007
Data analysis methods and techniques are revisited in the case of biological data sets. Particular emphasis is given to clustering and mining issues. Clustering is still a subject of active research in several fields such as statistics, pattern recognition, and machine learning.
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Effect of salidroside on the immune function of BCG-infected macrophages

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To Investigate the effects of salidroside (SAL) on the immune response of macrophages infected with BCG.Methods·RAW264.7 mouse macrophages were infected with BCG, and the experiments were divided into blank control (BCG), salidroside (SAL+BCG),
NI Shuyi, JIANG Zhao, WANG Zhongtao, HE Shumei   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Development of Bioinformatics Infrastructure for Genomics Research in H3Africa [PDF]

, 2017
Background: Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure.
Adebiyi, Ezekiel, Adebiyi, Marion O., Adeyemi, S., Ahmed, A., Ahmed, R., Akanle, B., Alibi, M., Armstrong, D. L., Aron, S., Ashanoz, E., Baichoo, S., Benkahla, A., Bishop, OzlemTastan, Brown, D. K., Chimusa, E., Fadlelmolak, F. M., Falola, O., Fatumo, S., Ghedira, Kais, Ghouila, Amel, Hazelhurst, S., Isewon, Itunuoluwa, Jung, S., Kassim, S. K., Kayondo, J. K., Mbiyavanga, M., Meintjes, A., Mohammed, S., Mosaku, Abayomi, Moussa, A., Muhammd, M., Mulder, Nicola J., Mungloo-Dilmohamud, Z., Nashiru, Oyekanmi, Odia, Trust, Okafor, A., Oladipo, O., Osamor, V. C., Oyelade, O. J., Panji, Sumir, Radouani, F., Sadki, K., Salifu, S. P., Souiai, O., Soyemi, J.   +44 more
core  

A Short Survey on Data Clustering Algorithms

, 2015
With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial analysis ...
Wong, Ka-Chun
core   +1 more source