Results 111 to 120 of about 22,135,367 (247)

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources

, 2022
S.268-270The Helmholtz Network for Bioinformatics (HNB) is a joint venture of eleven German bioinformatics research groups that offers convenient access to numerous bioinformatics resources through a single web portal.
Crass, T., Christensen, M., Claussen, H., Antes, I., Basekow, W., Bork, P., Buning, C., Gailus-Durner, V., Ernst, P., Ebeling, C.   +9 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Metabolomics Bioinformatics Analysis

, 2023
The basics of data processing are to convert the original data file into a representation to help easily access the characteristics of each observed ion. These characteristics include ion retention time and m/z time, as well as ion intensity measurements in each raw data file.
openaire   +2 more sources

Bioinformatic and functional analysis of TGFBR1 polymorphisms

Pharmacogenetics and Genomics, 2009
The transforming growth factor-beta (TGFB) pathway has substantial impact on cellular functions, cell proliferation, and apoptosis. We used bioinformatics, gene expression, and cell biological assays to evaluate the functionality of frequent inherited germline polymorphisms in the TGFB receptor 1 (TGFBR1).In an exploratory (n=55) and confirmatory (n ...
Schirmer, Markus Anton, Hoffmann, Arne O., Campean, Radu, Janke, Joerg H., Zidek, Laura M., Hoffmann, Marion, Kruse, Moritz, Sehrt, Daniel, Tzvetkov, Mladen Vassilev, Rave-Fraenk, Margret, Brockmoeller, Juergen   +10 more
openaire   +3 more sources

Symbolic Entropy of the Amplitude rather than the Instantaneous Frequency of EEG Varies in Dementia

Entropy, 2015
The dynamics of human electroencephalography (EEG) have been proved to be related to cognitive activities. This study separately assessed the two EEG components, amplitude and rhythm, aiming to capture their individual contributions to cognitive ...
Pei-Feng Lin, Jenho Tsao, Men-Tzung Lo, Chen Lin, Yi-Chung Chang   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Current progress and future opportunities in applications of bioinformatics for biodefense and pathogen detection: report from the Winter Mid-Atlantic Microbiome Meet-up, College Park, MD, January 10, 2018

Microbiome, 2018
The Mid-Atlantic Microbiome Meet-up (M3) organization brings together academic, government, and industry groups to share ideas and develop best practices for microbiome research.
Jacquelyn S. Meisel, Daniel J. Nasko, Brian Brubach, Victoria Cepeda-Espinoza, Jessica Chopyk, Héctor Corrada-Bravo, Marcus Fedarko, Jay Ghurye, Kiran Javkar, Nathan D. Olson, Nidhi Shah, Sarah M. Allard, Adam L. Bazinet, Nicholas H. Bergman, Alexis Brown, J. Gregory Caporaso, Sean Conlan, Jocelyne DiRuggiero, Samuel P. Forry, Nur A. Hasan, Jason Kralj, Paul M. Luethy, Donald K. Milton, Brian D. Ondov, Sarah Preheim, Shashikala Ratnayake, Stephanie M. Rogers, M. J. Rosovitz, Eric G. Sakowski, Nils Oliver Schliebs, Daniel D. Sommer, Krista L. Ternus, Gherman Uritskiy, Sean X. Zhang, Mihai Pop, Todd J. Treangen   +35 more
doaj   +1 more source

BioRuby: Bioinformatics software for the Ruby programming language [PDF]

, 2010
The BioRuby software toolkit contains a comprehensive set of free development tools and libraries for bioinformatics and molecular biology, written in the Ruby programming language.
Aerts, Jan, Raoul Bonnal, Jan Aerts, Prins, Pjotr, Nakao, M., Bonnal, Raoul, Prins, P., Goto, Naohisa, Pjotr Prins, Nakao, Mitsuteru, Katayama, T., Mitsuteru Nakao, Toshiaki Katayama, Naohisa Goto, Prins, J.C.P., Aerts, J., Goto, N., Bonnal, R., Katayama, A., Katayama, Toshiaki   +19 more
core   +2 more sources