Results 11 to 20 of about 2,333,106 (317)

BIOLOGICALLY ACTIVE OXADIAZOLE

open access: yesJournal of Drug Delivery and Therapeutics, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
openaire   +2 more sources

Exercise Serum Alters Genes Related Mitochondria in Cardiomyocyte Culture Cell

open access: yesJurnal Pendidikan Jasmani dan Olahraga, 2020
Exercise-induced hearth muscle adaptation is important for physiological process after exercise. This adaptation will ensure basal mitochondrial homeostasis and as a part of the mitochondria quality control.
Ronny Lesmana   +8 more
doaj   +1 more source

Naturally Occurring Yeasts Associated with Thaumatotibia leucotreta Can Enhance the Efficacy of the Cryptophlebia Leucotreta Granulovirus

open access: yesPathogens, 2023
Yeasts associated with lepidopteran pests have been shown to play a role in their survival, development, and oviposition preference. It has been demonstrated that combining these yeasts with existing biological control agents can enhance their efficacy ...
Marcel van der Merwe   +4 more
doaj   +1 more source

Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation

open access: yesJournal of Chemistry, 2017
Given the broad spectrum of biological uses of heteroaryl-acrylonitrile derivatives, it is necessary to find simple methods to synthesize and diversify this family of compounds.
Adriana V. Treuer   +2 more
doaj   +1 more source

Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

open access: yesMolecules, 2022
New target molecules, namely, 2-phenylamino-4-phenoxyquinoline derivatives, were designed using a molecular hybridization approach, which was accomplished by fusing the pharmacophore structures of three currently available drugs: nevirapine, efavirenz ...
Arthit Makarasen   +9 more
doaj   +1 more source

A Mild Synthesis of New Aryl Vinyl Ethers and Diethyl 1-[(Alkyl)(cyano)methyl]vinylphosphonates via the Substitution of a 2,3-Difunctional Allyl Bromide

open access: yesThe Scientific World Journal, 2014
A novel class of aryl vinyl ethers 3 and diethyl 3-cyano-3-alkylprop-1-en-2-ylphosphonates 4 has been prepared, respectively, from coupling reaction of diethyl 1-(bromomethyl)-2-cyanovinylphosphonate 2 with phenols and Gilman reagents.
Asma Fray   +3 more
doaj   +1 more source

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

open access: yesGenome Medicine, 2017
Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone.
Leif Väremo   +7 more
doaj   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

open access: yesKemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source

Providing the basis for a patient-centred and effective screening for cancer-related fatigue (MERLIN study): design of a longitudinal observational study

open access: yesBMJ Open, 2023
Introduction Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients’ quality of life and functioning.
Martina E Schmidt   +5 more
doaj   +1 more source

BIOLOGICAL ACTIVITY OF SUCCINIC ACIDS [PDF]

open access: yesBiotechnologia Acta, 2018
The aim of the research was to detect the biological activity of aqueous solutions of various samples of amber from the Trancedniestria province, and to characterize their effect on the physiological processes of higher plants.
N. Ya. Levchyck   +5 more
doaj   +1 more source

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