Results 11 to 20 of about 2,249,976 (224)

Zn(II) binding to pramlintide results in a structural kink, fibril formation and antifungal activity

Scientific Reports, 2022
The antimicrobial properties of amylin, a 37-amino acid peptide hormone, co-secreted with insulin from the pancreas, are far less known than its antidiabetic function.
Dorota Dudek, Emilia Dzień, Joanna Wątły, Agnieszka Matera-Witkiewicz, Aleksandra Mikołajczyk, Agata Hajda, Joanna Olesiak-Bańska, Magdalena Rowińska-Żyrek   +7 more
doaj   +1 more source

Naturally Occurring Yeasts Associated with Thaumatotibia leucotreta Can Enhance the Efficacy of the Cryptophlebia Leucotreta Granulovirus

Pathogens, 2023
Yeasts associated with lepidopteran pests have been shown to play a role in their survival, development, and oviposition preference. It has been demonstrated that combining these yeasts with existing biological control agents can enhance their efficacy ...
Marcel van der Merwe, Michael D. Jukes, Caroline Knox, Sean D. Moore, Martin P. Hill   +4 more
doaj   +1 more source

Exercise Serum Alters Genes Related Mitochondria in Cardiomyocyte Culture Cell

Jurnal Pendidikan Jasmani dan Olahraga, 2020
Exercise-induced hearth muscle adaptation is important for physiological process after exercise. This adaptation will ensure basal mitochondrial homeostasis and as a part of the mitochondria quality control.
Ronny Lesmana, Wibowo Budi Prasetyo, Hamidie Ronald Daniel Ray, Vita Murniati Tarawan, Hanna Goenawan, Iwan Setiawan, Yuni Susanti Pratiwi, Nova Sylviana Juliati, Unang Supratman   +8 more
doaj   +1 more source

Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Molecules, 2022
New target molecules, namely, 2-phenylamino-4-phenoxyquinoline derivatives, were designed using a molecular hybridization approach, which was accomplished by fusing the pharmacophore structures of three currently available drugs: nevirapine, efavirenz ...
Arthit Makarasen, Suwicha Patnin, Pongsit Vijitphan, Nanthawan Reukngam, Panita Khlaychan, Mayuso Kuno, Pakamas Intachote, Busakorn Saimanee, Suchada Sengsai, Supanna Techasakul   +9 more
doaj   +1 more source

Biological markers of disease activity in inflammatory bowel diseases

Gastroenterology Review, 2023
Inflammatory bowel diseases (IBD) are chronic intestinal conditions of multifactorial aetiology including genetic susceptibility, immunological impairment, dysbiosis, and environmental factors.
Edyta Szymanska, Sylwia Szymanska, Maciej Dadalski, Jaroslaw Kierkus   +3 more
doaj   +1 more source

Providing the basis for a patient-centred and effective screening for cancer-related fatigue (MERLIN study): design of a longitudinal observational study

BMJ Open, 2023
Introduction Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients’ quality of life and functioning.
Martina E Schmidt, Karen Steindorf, Bernhard Holzner, Patricia Blickle, Alexander Haussmann, Anne Katrin Berger   +5 more
doaj   +1 more source

Future Directions for Active Matter on Ordered Substrates [PDF]

EPL 139, 27001 (2022), 2022
Active matter is a term encompassing particle-based assemblies with some form of self-propulsion, including certain biological systems as well as synthetic systems such as artificial colloidal swimmers, all of which can exhibit a remarkable variety of new kinds of nonequilibrium phenomena.
arxiv   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

Kemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source

Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation

Journal of Chemistry, 2017
Given the broad spectrum of biological uses of heteroaryl-acrylonitrile derivatives, it is necessary to find simple methods to synthesize and diversify this family of compounds.
Adriana V. Treuer, Pedro De-La-Torre, Margarita I. Gutiérrez   +2 more
doaj   +1 more source

Biological Activity of Hexaazaisowurtzitane Derivatives

Molecules, 2023
Biologically active compounds of natural or synthetic origin have a complex structure and generally contain various structural groups among which polycyclic cage amines are found.
Daria A. Kulagina, Sergey V. Sysolyatin, Svetlana G. Krylova, Elena A. Kiseleva, Tatiana N. Povetyeva, Elena P. Zueva, Valeria V. Eremina, Natalia A. Alekseeva, Svetlana V. Strokova, Nikolai I. Suslov, Vadim V. Zhdanov   +10 more
doaj   +1 more source