Results 91 to 100 of about 3,274,267 (305)

Two-dimensional system based on organic and functional impairment with aging for precisely assessing risk factors in chronic disease

open access: yesArchives of Medical Science, 2019
Introduction The aim of the study was to establish a two-dimensional system based on organic and functional biological age (BA) using a biomarker of organic and functional impairment with aging for precisely assessing roles of natural aging and other ...
Wang Cengfang, Gao Hanboya, Liu Hui
doaj   +1 more source

Explaining Differences in Education between Foster Children and Biological Children: a Sibling Rivalry Approach. Some Evidence from Indonesia [PDF]

open access: yes
This paper aims at explaining differences in education between foster-children and the biological children of their new household by differences in return to education as suggested by the human capital investment model. Defining this return by the amount
Karine Marazyan
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Biological Age Revisited [PDF]

open access: yesThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013
Arnold, Mitnitski, Kenneth, Rockwood
openaire   +2 more sources

Old Age: Biologic Versus Chronologic

open access: yesJournal of Clinical Oncology, 2007
We read with great interest the article by Goldberg et al1 reporting the results of a “Pooled Analysis of Safety and Efficacy of Oxaliplatin Plus Fluorouracil/Leucovorin Administered Bimonthly in Elderly Patients With Colorectal Cancer” published in the September 1, 2006, issue of the Journal of Clinical Oncology.
Gelibter, Alain J   +6 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Biological Age as a New Risk Factor for Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus

open access: yesOftalʹmologiâ
For the prevention of diabetic retinopathy, it is important to study risk factors, among which, along with the duration of type 2 diabetes mellitus, the level of glycemia, obesity, chronological age is indicated, but biological age is not considered as a
N. M. Agarkov   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Beginning of Senior Career in Team Sport Is Affected by Relative Age Effect

open access: yesFrontiers in Psychology, 2019
Many previous studies in national team sports did not report evidence about relative age effect (RAE) in senior categories. This study aimed for the first time to determine if the RAE may specifically affect the early, but not the late, phase of senior ...
Corrado Lupo   +5 more
doaj   +1 more source

On engineering reliability concepts and biological aging [PDF]

open access: yes
Some stochastic approaches to biological aging modeling are studied. We assume that an organism acquires a random resource at birth. Death occurs when the accumulated dam-age (wear) exceeds this initial value, modeled by the discrete or continuous random
Maxim S. Finkelstein
core  

Home - About - Disclaimer - Privacy