Results 101 to 110 of about 1,535,781 (307)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Beginning of Senior Career in Team Sport Is Affected by Relative Age Effect

Frontiers in Psychology, 2019
Many previous studies in national team sports did not report evidence about relative age effect (RAE) in senior categories. This study aimed for the first time to determine if the RAE may specifically affect the early, but not the late, phase of senior ...
Corrado Lupo, Gennaro Boccia, Alexandru Nicolae Ungureanu, Riccardo Frati, Roberto Marocco, Paolo Riccardo Brustio   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The association between SII and aging: evidence from NHANES 1999–2018

Frontiers in Public Health
BackgroundThe study aimed to examine the association between the systemic immune-inflammation index (SII), a contemporary metric of systemic inflammatory response, and biological aging, which are closely interconnected processes.MethodsThis cross ...
Nanbu Wang, Lian Ren, Ziyuan Li, Yunhao Hu, Jingpei Zhou, Quan Sun, Bin Pei, Xinyu Li, Wanqing Peng, Jinyan Yu, Renhui Zhao, Ziting Huang, Zhenhu Chen, Guoxin Huang   +13 more
doaj   +1 more source

Dental Age Estimation Course Handbook [PDF]

, 2020
Age is knowledge, both indispensable and invaluable information for all beings. Age is a measure from birth to a specific time point; it is mostly expressed in years.
Arofi Kurniawan, -, An'nissa Chusida, -, B. Soegeng Herjadi, -, Rizky Merdietio B, -, Maria Istiqomah Marini, -, Haryono Utomo, -, Mieke Sylvia Margaretha Amiatun Ruth, -, Agung Sosiawan, -, Beta Novia Rizky, -   +8 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Using Biological Age to Predict Cognitive Performance

, 2023
Chronological age (i.e., time since birth) is known to be a major predictor for lower cognitive performance and decline. Although the passing of time is easily measured and convenient to collect, chronological age alone cannot explain why some 60-year ...
Daisy V Zavala, Giancarlo Pasquini, Christopher Gerald Engeland, Kerry Reid, Krishna Veeramah, Jennifer Graham-Engeland, Shyamalika Gopalan, Martin Sliwinski, Stacey Scott, Kristin Bernard   +9 more
core   +1 more source

Biological processes associated with age.

, 2016
Based on statistical significance i.e. -log (P value) as determined by IPA analysis, the biological processes positively (A) and negatively (B) associated with age are shown.
Rick W. Wright (3172104), Linda J. Sandell (620198), Muhammad Farooq Rai (202705), Robert H. Brophy (3172101), Bo Zhang (6559)   +4 more
core   +1 more source

Circadian and ultradian NREM-REM sleep modulation of dream recall : effects of age and spectral activity [PDF]

, 2011
This thesis deals with the electrophysiological correlates of sleep prior to dream recall and the age-related effects on dream processing. The dual NREM/REM sleep cycle and the circadian modulation of REM sleep sum to generate dream processing.
Laxhmi Chellappa, Sarah
core   +1 more source