Results 81 to 90 of about 1,535,781 (307)
Common methods of biological age estimation
, 2017 Linpei Jia,1–3 Weiguang Zhang,2,3 Xiangmei Chen1–3 1Department of Nephrology, Second Hospital of Jilin University, Changchun, Jilin Province, 2Department of Nephrology, Chinese People’s Liberation Army General Hospital, Beijing, 3State
Zhang W, Chen X, Jia L
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Using Biological Age to Predict Cognitive Performance
, 2022 Chronological age (i.e., time since birth) is known to be a major predictor for lower cognitive performance and decline. Although the passing of time is easily measured and convenient to collect, chronological age alone cannot explain why some 60-year ...
Daisy V Zavala +9 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
On engineering reliability concepts and biological aging [PDF]
Some stochastic approaches to biological aging modeling are studied. We assume that an organism acquires a random resource at birth. Death occurs when the accumulated dam-age (wear) exceeds this initial value, modeled by the discrete or continuous random
Maxim S. Finkelstein
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Anti-aging by means of physical education (on example of swimming)
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2016 Purpose: to work out complex anti-aging program to find its influence on biological age and tem of elderly persons’ ageing. Material: in experiment 78 persons (44 men and 34 women with accelerated organism’s ageing) participated.
N.V. Fedyniak, B.M. Mytskan
doaj +1 more source
The results are part of a project carried out at the Complutense University of Madrid in collaboration with KUYDA-T®. KUYDA-T® provided financial support.Aging involves immune system deterioration (immunosenescence) and increased oxidative stress, both ...
Fuente Del Rey, María Mónica De La +3 more
core +1 more source
Early-Life Intelligence Predicts Midlife Biological Age
, 2016 Objectives. Early-life intelligence has been shown to predict multiple causes of death in populations around the world. This finding suggests that intelligence might influence mortality through its effects on a general process of physiological ...
Caspi, Avshalom +21 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source