Results 81 to 90 of about 9,268,590 (315)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The mediating role of caffeine and biological age in the association between dietary index for gut microbiota and osteoporosis

Frontiers in Nutrition
BackgroundThe Dietary Index for Gut Microbiota (DI-GM) is a novel metric developed to evaluate the diversity of intestinal microbiota. However, its relationship with osteoporosis remains uncertain.MethodsThis study utilized data from the National Health ...
Yaxiong Li, Hong Cao, Jingyuan Zhang
doaj   +1 more source

Two-dimensional system based on organic and functional impairment with aging for precisely assessing risk factors in chronic disease

Archives of Medical Science, 2019
Introduction The aim of the study was to establish a two-dimensional system based on organic and functional biological age (BA) using a biomarker of organic and functional impairment with aging for precisely assessing roles of natural aging and other ...
Wang Cengfang, Gao Hanboya, Liu Hui
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1943

, 1944
Annual report of the Marine Biological Laboratory in Woods Hole. 1943.
Marine Biological Laboratory (Woods Hole MA)
core  

Annual Report - Marine Biological Laboratory, 1933 [PDF]

, 1933
Annual report of the Marine Biological Laboratory in Woods Hole. 1933.
Marine Biological Laboratory (Woods Hole MA)
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1888

, 1889
Annual report of the Marine Biological Laboratory in Woods Hole. 1888.
Marine Biological Laboratory (Woods Hole MA)
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Biological Age as a New Risk Factor for Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus

Oftalʹmologiâ
For the prevention of diabetic retinopathy, it is important to study risk factors, among which, along with the duration of type 2 diabetes mellitus, the level of glycemia, obesity, chronological age is indicated, but biological age is not considered as a
N. M. Agarkov, O. L. Fabrikantov, I. V. Lev   +2 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1892

, 1892
Annual report of the Marine Biological Laboratory in Woods Hole. 1892.
Marine Biological Laboratory (Woods Hole MA)
core