Results 61 to 70 of about 1,535,781 (307)

Biological Age Imputation by Data Depth

, 2023
The biological age is an indicator of the functional condition of an individual’s body. Unlike the chronological age, which just measures the time from birth, the biological age of a human is also affected by its medical condition, life habits, some ...
Cabras, Stefano, Durbán, María, Cascos, Ignacio, Ochoa, Maicol, Guerrero, Vanesa, D’Auria, Bernardo   +5 more
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Theories of biological aging

Experimental Gerontology, 1985
Experimental Gerontology 20 (1985) 145-159. doi:10.1016/0531-5565(85)90032-4 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:36 ; DOI:10.1016/0531-5565(85)90032-4 ; Page Range: 145 ...
Center for Gerontological Studies, University of Florida 3357 GPA, Gaineville, Florida 32611 USA ( host institution ), Hayflick, Leonard ( author )   +1 more
openaire   +3 more sources

ExplaiNAble BioLogical Age (ENABL Age): an artificial intelligence framework for interpretable biological age

The Lancet Healthy Longevity, 2023
Biological age is a measure of health that offers insights into ageing. The existing age clocks, although valuable, often trade off accuracy and interpretability. We introduce ExplaiNAble BioLogical Age (ENABL Age), a computational framework that combines machine-learning models with explainable artificial intelligence (XAI) methods to accurately ...
Wei, Qiu, Hugh, Chen, Matt, Kaeberlein, Su-In, Lee   +3 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Biological maturity but not relative age biases exist in female international youth soccer players relative to the general population [PDF]

This study investigated the extent to which biological maturity and relative age biases existed and varied with chronological age in female international youth soccer players relative to the general population.
Cian Sweeney, Jack Hickey, Áine MacNamara, Sweeney, Liam, Tommy R Lundberg, Lundberg, Tommy, Hickey, Jack, MacNamara, Áine, Liam Sweeney, Sweeney, Cian   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Kindlin-1 promotes gastric cancer cell motility through the Wnt/β-catenin signaling pathway

Scientific Reports
Despite advances in gastric cancer diagnosis and treatment, its prognosis remains poor owing to aggressive tumor progression and metastasis. As understanding the relevant molecular mechanisms is essential to effectively improve patient outcomes, we ...
Jun-Ho Jang, Jiyoon Jung, Hyeon-Gu Kang, Woong Kim, Won-Jin Kim, Hana Lee, Ju Yeon Cho, Ran Hong, Jeong Won Kim, Joon-Yong Chung, Kyung-Hee Chun, Seok-Jun Kim   +11 more
doaj   +1 more source