Results 51 to 60 of about 1,535,781 (307)

Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders

Current Issues in Molecular Biology
Neuroinflammation is a complex and dynamic response of the central nervous system (CNS) to injury, infection, and disease. While acute neuroinflammation plays a protective role by facilitating pathogen clearance and tissue repair, chronic and ...
Mi Eun Kim, Jun Sik Lee
doaj   +1 more source

Cyclic Colonization in Predictably Ephemeral Habitats: A Template for Biological Control in Annual Crop Systems

, 1997
Biological control strategies that were developed for orchards and forests have had limited success in controling pests in annual crop systems (ACSs). In this paper I will argue that an accurate characterization of the habitat template of ACSs will be a ...
Wissinger, Scott A.
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

IL-10–STAT3-Dependent Transcriptional Regulation in Microglia: Alzheimer’s Disease and Neuroinflammation

Biomedicines
Interleukin-10 (IL-10) is a key immunoregulatory cytokine that suppresses inflammatory gene transcription in myeloid cells through signal transducer and activator of transcription 3 (STAT3). In Alzheimer’s disease and neuroinflammation, microglia express
Mi Eun Kim, Jun Sik Lee
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Utility of the Age Discrepancy between Frailty-Based Biological Age and Expected Life Age in Patients with Urological Cancers

, 2022
Background: The estimation of biological age is challenging in patients with cancers. We aimed to investigate frailty-based biological ages using frailty-discriminant scores (FDS) and examined the effect of biological-expected life age discrepancy on the
Takuro Iwane, Takahiro Yoneyama, Okita, Kazutaka, Teppei Okamoto, Daisuke Noro, Hayato Yamamoto, Okamoto, Teppei, Naoki Fujita, Yoneyama, Takahiro, Horiguchi, Hirotaka, Tanaka, Toshikazu, Osamu Soma, Yasuhiro Hashimoto, Noro, Daisuke, Hirotaka Horiguchi, Uemura, Nozomi, Togashi, Kyo, Nozomi Uemura, Kazutaka Okita, Chikara Ohyama, Hatakeyama, Shingo, Soma, Osamu, Hashimoto, Yasuhiro, Iwane, Takuro, Kyo Togashi, Shingo Hatakeyama, Fujita, Naoki, Yamamoto, Hayato, Ohyama, Chikara, Toshikazu Tanaka   +29 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Motor performance of young soccer players depending on biological age

Exercise and Quality of Life, 2017
The main purpose of our article was to broaden the knowledge of the level of the motor performance of young soccer players in puberty, taking into account their biological age.
Miroslav Holienka, Matej Babic, Ladislava Doležajová, Peter Šelinger, Eva Musilová   +4 more
doaj   +1 more source

The challenges of estimating biological age

eLife, 2020
A comparison of nine different approaches over a period of 20 years reveals the most promising indicators for biological age.
Alexey Moskalev
doaj   +1 more source

The Use of Retinal Microvascular Function and Telomere Length in Age and Blood Pressure Prediction in Individuals with Low Cardiovascular Risk

Cells, 2022
Ageing represents a major risk factor for many pathologies that limit human lifespan, including cardiovascular diseases. Biological ageing is a good biomarker to assess early individual risk for CVD.
Hala Shokr, Victoria Lush, Irundika HK Dias, Anikó Ekárt, Gustavo De Moraes, Doina Gherghel   +5 more
doaj   +1 more source