Results 41 to 50 of about 3,274,267 (305)

Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders

Current Issues in Molecular Biology
Neuroinflammation is a complex and dynamic response of the central nervous system (CNS) to injury, infection, and disease. While acute neuroinflammation plays a protective role by facilitating pathogen clearance and tissue repair, chronic and ...
Mi Eun Kim, Jun Sik Lee
doaj   +1 more source

Examination of the Dimensions of Biological Age

Frontiers in Genetics, 2019
The concept of biological age has been used more and more frequently in aging research in attempts to measure the progress of the biological aging process as opposed to the simple passage of time.
S. Michal Jazwinski, Sangkyu Kim
doaj   +1 more source

Radiocarbon analysis of modern skeletal remains to determine year of birth and death: a case study [PDF]

, 2015
To aid in the development of a biological profile for human remains found in Collyhurst, Manchester, England we undertook 14C analysis of tooth enamel, tooth collagen and bone collagen on behalf of Greater Manchester Police.
Ainscough, L.A.N., Cook, G.T., Dunbar, E.   +2 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

IL-10–STAT3-Dependent Transcriptional Regulation in Microglia: Alzheimer’s Disease and Neuroinflammation

Biomedicines
Interleukin-10 (IL-10) is a key immunoregulatory cytokine that suppresses inflammatory gene transcription in myeloid cells through signal transducer and activator of transcription 3 (STAT3). In Alzheimer’s disease and neuroinflammation, microglia express
Mi Eun Kim, Jun Sik Lee
doaj   +1 more source

Paternal and Maternal History of Myocardial Infarction and Cardiovascular Diseases Incidence in a Dutch Cohort of Middel-Aged Persons [PDF]

, 2011
Background - A positive parental history of myocardial infarction (MI) is an independent risk factor for cardiovascular diseases (CVD). However, different definitions of parental history have been used.
Dis, I., van, Kromhout, D., Boer, J.M.A., Geleijnse, J.M., Verschuren, W.M.M.   +4 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Motor performance of young soccer players depending on biological age

Exercise and Quality of Life, 2017
The main purpose of our article was to broaden the knowledge of the level of the motor performance of young soccer players in puberty, taking into account their biological age.
Miroslav Holienka, Matej Babic, Ladislava Doležajová, Peter Šelinger, Eva Musilová   +4 more
doaj   +1 more source

The challenges of estimating biological age

eLife, 2020
A comparison of nine different approaches over a period of 20 years reveals the most promising indicators for biological age.
Alexey Moskalev
doaj   +1 more source

The Use of Retinal Microvascular Function and Telomere Length in Age and Blood Pressure Prediction in Individuals with Low Cardiovascular Risk

Cells, 2022
Ageing represents a major risk factor for many pathologies that limit human lifespan, including cardiovascular diseases. Biological ageing is a good biomarker to assess early individual risk for CVD.
Hala Shokr, Victoria Lush, Irundika HK Dias, Anikó Ekárt, Gustavo De Moraes, Doina Gherghel   +5 more
doaj   +1 more source