Results 21 to 30 of about 9,268,590 (315)

RapC Is Involved in the Development of Dictyostelium Through the Regulation of Autophagy and Calcium Signaling

Cells
RapC is a Rap-subfamily small GTPase in Dictyostelium whose developmental function remains largely uncharacterized. Upon starvation, individual amoebae aggregate and undergo morphogenetic transitions to ultimately produce a fruiting body, a process ...
Nara Han, Uri Han, Dahyeon Kim, Wonbum Kim, Taeck Joong Jeon   +4 more
doaj   +1 more source

A new complex marker for elevated arterial stiffnes estimation

Атеросклероз, 2020
Age is one of the well known strongest risk factors of cardiovascular diseases (CVD). At the same time, vessel age or arterial wall stiffness is one of the major determinants of so called biological age.
V. A. Metelskaya, N. V. Gomyranova, E. B. Yarovaya, O. M. Drapkina   +3 more
doaj   +1 more source

Biological mechanisms of ageing [PDF]

Eye, 1987
In a short review of the theories or proposed biological mechanisms of ageing it is necessary to be very selective in the ideas which are included or rejected. Although many theories of ageing are advanced in the literature a high proportion can be considered to be special cases of a previous hypothesis. No one individual theory satisfactorily explains
openaire   +2 more sources

Nhe1 is required for directional sensing in vegetative Dictyostelium cell migration

Cell Adhesion & Migration
Na+/H+ exchanger 1 (Nhe1) is a crucial regulator of pH homeostasis and the present study demonstrates that Nhe1 is required for directional sensing in vegetative Dictyostelium cell migration.
Uri Han, Nara Han, Taeck Joong Jeon
doaj   +1 more source

Mathematical model of the bone biological age based on the bone mineral density and quality indicex and Ukrainian FRAX model

Bolʹ, Sustavy, Pozvonočnik, 2022
Background. It is well-known that with aging there is a loss of bone mass and its strength, which leads to the development of osteoporosis and its complications.
N.V. Grygorieva, H.S. Dubetska, N.M. Koshel, A.V. Pisaruk, I.A. Antoniuk-Shcheglova   +4 more
doaj   +1 more source

Progress in biological age research

Frontiers in Public Health, 2023
Biological age (BA) is a common model to evaluate the function of aging individuals as it may provide a more accurate measure of the extent of human aging than chronological age (CA).
Zhe Li, Zhe Li, Weiguang Zhang, Yuting Duan, Yuting Duan, Yue Niu, Yizhi Chen, Yizhi Chen, Xiaomin Liu, Zheyi Dong, Ying Zheng, Xizhao Chen, Zhe Feng, Yong Wang, Delong Zhao, Xuefeng Sun, Guangyan Cai, Hongwei Jiang, Xiangmei Chen   +18 more
doaj   +1 more source

Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

Neurobiology of Disease, 2005
We have shown that over-expression of human tau (0N3R) in Drosophila larval motor neurons causes significant morphological and functional disruption to the neuromuscular junctions (NMJs).
Francis C. Chee, Amritpal Mudher, Matthew F. Cuttle, Tracey A. Newman, Daniel MacKay, Simon Lovestone, David Shepherd   +6 more
doaj   +1 more source

A Targeted Epigenetic Clock for the Prediction of Biological Age

Cells, 2022
Epigenetic clocks were initially developed to track chronological age, but accumulating evidence indicates that they can also predict biological age.
Noémie Gensous, Claudia Sala, Chiara Pirazzini, Francesco Ravaioli, Maddalena Milazzo, Katarzyna Malgorzata Kwiatkowska, Elena Marasco, Sara De Fanti, Cristina Giuliani, Camilla Pellegrini, Aurelia Santoro, Miriam Capri, Stefano Salvioli, Daniela Monti, Gastone Castellani, Claudio Franceschi, Maria Giulia Bacalini, Paolo Garagnani   +17 more
doaj   +1 more source

Prevalence of Phototherapy in the Age of Biologics [PDF]

Dermatology, 2018
<b><i>Background:</i></b> The prevalence of narrow-band ultraviolet B (NB-UVB) use in Europe for moderate and severe psoriasis is unknown, because national registries for psoriasis do not monitor this treatment. <b><i>Objectives:</i></b> To quantify the use of phototherapy, biologics or conventional ...
Calzavara-Pinton P, Zanca A, Arisi M, Rossi MT, Zane C, Venturini M, Ortel B   +6 more
openaire   +4 more sources

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source