Results 1 to 10 of about 317,209 (276)
An epigenetic clock for human skeletal muscle [PDF]
Journal of Cachexia, Sarcopenia and Muscle, 2020 Background Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues.
Sarah Voisin +15 more
doaj +16 more sources
Epigenetic clock as a correlate of anxiety [PDF]
NeuroImage: Clinical, 2020 DNA methylation changes consistently throughout life and age-dependent alterations in DNA methylation can be used to estimate one’s epigenetic age. Post-mortem studies revealed higher epigenetic age in brains of patients with major depressive disorder ...
Klára Marečková +8 more
doaj +5 more sources
A Targeted Epigenetic Clock for the Prediction of Biological Age [PDF]
Cells, 2022 Epigenetic clocks were initially developed to track chronological age, but accumulating evidence indicates that they can also predict biological age.
Noémie Gensous +17 more
doaj +4 more sources
Developmental Tuning of Epigenetic Clock [PDF]
Frontiers in Genetics, 2018 Research in the field of gerontology has traditionally focused on later life stages. There is increasing evidence, however, that both the rate of age-related functional decline and the later-life health status can be programmed during early development ...
Alexander Vaiserman
doaj +5 more sources
An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology
Frontiers in Genetics, 2021 Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
Ben J. Hayes +7 more
doaj +3 more sources
Epigenetic clock analysis of blood samples in drug-naive first-episode schizophrenia patients [PDF]
BMC Psychiatry, 2023 Background Schizophrenia (SCZ) is a severe and chronic psychiatric disorder with premature age-related physiological changes. However, numerous previous studies examined the epigenetic age acceleration in SCZ patients and yielded inconclusive results. In
Zongchang Li +6 more
doaj +2 more sources
A Novel Loop: Mutual Regulation Between Epigenetic Modification and the Circadian Clock
Frontiers in Plant Science, 2019 In response to periodic environmental fluctuations generated by the rotation of the earth, nearly all organisms have evolved an intrinsic timekeeper, the circadian clock, which can maintain approximate 24-h rhythmic oscillations in biological processes ...
Shenxiu Du +3 more
doaj +3 more sources
Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids
Communications Biology, 2021 Larison et al. report epigenetic aging models in plains zebras (Equus quagga) using the epigenetic clock and epigenetic pacemaker approaches. Their epigenetic clock allows age to be accurately estimated in endangered sister species, and the pacemaker ...
Brenda Larison +13 more
doaj +1 more source
Neurobiology of Stress, 2021 Background: Studies reporting accelerated ageing in children with affective disorders or maltreatment exposure have relied on algorithms for estimating epigenetic age derived from adult samples.
Felix Dammering +11 more
doaj +1 more source
Evaluation of pediatric epigenetic clocks across multiple tissues
Clinical Epigenetics, 2023 Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang +28 more
doaj +1 more source