Results 31 to 40 of about 2,105 (236)

Epigenetic Clock: DNA Methylation in Aging [PDF]

open access: yesStem Cells International, 2020
Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years. In recent decades, with the rapid development of biology, scientists have shown that epigenetic modifications, especially DNA methylation, are key regulators involved in this process ...
Shuang Jiang, Yuchen Guo
openaire   +3 more sources

Effect of metformin on the epigenetic age of peripheral blood in patients with diabetes mellitus

open access: yesFrontiers in Genetics, 2022
Background: Metformin has been proven to have an antiaging effect. However, studies on how metformin affects global epigenetic regulation and its effect on the epigenetic clock in diabetes mellitus (DM) patients are limited.
Man Li, Litao Bao, Ping Zhu, Shuxia Wang
doaj   +1 more source

Cardiovascular health and four epigenetic clocks

open access: yesClinical Epigenetics, 2022
Abstract Background Cardiovascular health (CVH) was defined by the American Heart Association as an integrative idealness of seven clinical or lifestyle factors. Based on populations of European ancestry, recent studies have shown that ideal CVH is associated with a slower aging rate. The aging rate is measured by levels
Yun-Hsiang Lo, Wan-Yu Lin
openaire   +2 more sources

DataSheet1_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.PDF

open access: yes, 2021
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250)   +7 more
core   +1 more source

An epigenetic clock controls aging [PDF]

open access: yesBiogerontology, 2015
We are accustomed to treating aging as a set of things that go wrong with the body. But for more than twenty years, there has been accumulating evidence that much of the process takes place under genetic control. We have seen that signaling chemistry can make dramatic differences in life span, and that single molecules can significantly affect ...
openaire   +3 more sources

Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

open access: yesGenome Biology, 2019
Background Epigenetic clocks are mathematical models that predict the biological age of an individual using DNA methylation data and have emerged in the last few years as the most accurate biomarkers of the aging process.
Daniel E. Martin-Herranz   +9 more
doaj   +1 more source

DataSheet2_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.CSV

open access: yes, 2021
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250)   +7 more
core   +1 more source

Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination

open access: yesFrontiers in Genetics, 2022
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence suggest that severe COVID-19 is associated with durable scars to the epigenome.
Alina P. S. Pang   +15 more
doaj   +1 more source

Table1_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.XLSX

open access: yes, 2021
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250)   +7 more
core   +1 more source

How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence [PDF]

open access: yes, 2022
This study investigated the recently reported association between alcohol dependence and accelerated ageing and the potential effects of abstinence and relapse on DNA methylation status using Levine's epigenetic clock to estimate DNA methylation age in ...
Friedel, Eva   +8 more
core   +3 more sources

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