Results 31 to 40 of about 2,105 (236)
Epigenetic Clock: DNA Methylation in Aging [PDF]
Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years. In recent decades, with the rapid development of biology, scientists have shown that epigenetic modifications, especially DNA methylation, are key regulators involved in this process ...
Shuang Jiang, Yuchen Guo
openaire +3 more sources
Effect of metformin on the epigenetic age of peripheral blood in patients with diabetes mellitus
Background: Metformin has been proven to have an antiaging effect. However, studies on how metformin affects global epigenetic regulation and its effect on the epigenetic clock in diabetes mellitus (DM) patients are limited.
Man Li, Litao Bao, Ping Zhu, Shuxia Wang
doaj +1 more source
Cardiovascular health and four epigenetic clocks
Abstract Background Cardiovascular health (CVH) was defined by the American Heart Association as an integrative idealness of seven clinical or lifestyle factors. Based on populations of European ancestry, recent studies have shown that ideal CVH is associated with a slower aging rate. The aging rate is measured by levels
Yun-Hsiang Lo, Wan-Yu Lin
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DataSheet1_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.PDF
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250) +7 more
core +1 more source
An epigenetic clock controls aging [PDF]
We are accustomed to treating aging as a set of things that go wrong with the body. But for more than twenty years, there has been accumulating evidence that much of the process takes place under genetic control. We have seen that signaling chemistry can make dramatic differences in life span, and that single molecules can significantly affect ...
openaire +3 more sources
Background Epigenetic clocks are mathematical models that predict the biological age of an individual using DNA methylation data and have emerged in the last few years as the most accurate biomarkers of the aging process.
Daniel E. Martin-Herranz +9 more
doaj +1 more source
DataSheet2_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.CSV
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250) +7 more
core +1 more source
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence suggest that severe COVID-19 is associated with durable scars to the epigenome.
Alina P. S. Pang +15 more
doaj +1 more source
Table1_An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology.XLSX
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
James P. Copley (11722250) +7 more
core +1 more source
How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence [PDF]
This study investigated the recently reported association between alcohol dependence and accelerated ageing and the potential effects of abstinence and relapse on DNA methylation status using Levine's epigenetic clock to estimate DNA methylation age in ...
Friedel, Eva +8 more
core +3 more sources

