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An epigenetic clock for Xenopus tropicalis [PDF]
npj AgingDNA methylation clocks have been widely used for accurate age prediction, but most studies have been carried out on mammals. Here we present an epigenetic clock for the aquatic frog Xenopus tropicalis, a widely used model organism in developmental ...
Bennett, Ronan
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An Epigenetic Clock for Accurate Age Prediction in Atlantic Cod Populations for Improved Fisheries Management [PDF]
Mol Ecol Resour13 pages, 4 figuresFisheries management relies on accurate stock assessments, which in turn depend on precise age information. Recent molecular tools called ‘epigenetic clocks’ harness age-related DNA methylation changes to build accurate and precise age-
Kasmi, Yasinne +5 more
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Exploring a targeted epigenetic clock based on mortality-associated CpGs as a potential biomarker for frailty [PDF]
Clinical EpigeneticsBackground Age-related DNA methylation changes are promising biomarkers to track the individual aging process. Particularly second-generation epigenetic clocks capture aspects of biological age more accurately, but the requirement of genome wide profiles
Jonathan Awuah +6 more
doaj +2 more sources
Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study [PDF]
Clinical EpigeneticsBackground Biological age, especially epigenetic age derived from the epigenetic clock, is a significant measure of aging, considering the differences in aging rates among individuals.
Masatoshi Nagata +6 more
doaj +2 more sources
Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]
, 2015 The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S. +16 more
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Development of an epigenetic clock to predict visual age progression of human skin [PDF]
Frontiers in Aging, 2023 Aging is a complex process characterized by the gradual decline of physiological functions, leading to increased vulnerability to age-related diseases and reduced quality of life.
Agata Bienkowska +11 more
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Epigenetic Clocks and Programmatic Aging
Ageing Research Reviews, 2023 The last decade has seen remarkable progress in the characterization of methylation clocks that track biological age in humans and many other mammalian species. While the biological processes of aging that underlie these clocks have remained unclear, several clues have pointed to a link to developmental mechanisms.
David Gems +2 more
openaire +3 more sources
, 2012 Files include digitized sound recordings of an interview with John Percey Clock [rank unknown] and Lawrence K. Montgomery [rank unknown] who served in Company K, 339th Infantry, interviewed by John Robert Clock June 25, 1978. Transcript of interview is
Polar Bear Project, Bentley Historical Library
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An evolutionary epigenetic clock in plants
Science, 2023 Molecular clocks are the basis for dating the divergence between lineages over macroevolutionary timescales (~10 5 to 10 8 years). However, classical DNA-based clocks tick too slowly to inform us about the recent past.
Yao, N. +12 more
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Calibrating epigenetic clocks with training data error
Evolutionary Applications, 2023 Animal age data are valuable for management of wildlife populations. Yet, for most species, there is no practical method for determining the age of unknown individuals.
Benjamin Mayne +2 more
doaj +1 more source