Results 21 to 30 of about 2,105 (236)
Evaluation of pediatric epigenetic clocks across multiple tissues
Clinical Epigenetics, 2023 Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang +28 more
doaj +1 more source
An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology
Frontiers in Genetics, 2021 Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
Ben J. Hayes +7 more
doaj +1 more source
Calibrating epigenetic clocks with training data error
Evolutionary Applications, 2023 Animal age data are valuable for management of wildlife populations. Yet, for most species, there is no practical method for determining the age of unknown individuals.
Benjamin Mayne +2 more
doaj +1 more source
Dynamic epigenetic age mosaicism in the human atherosclerotic artery
PLoS ONE, 2022 Accelerated epigenetic ageing, a promising marker of disease risk, has been detected in peripheral blood cells of atherosclerotic patients, but evidence in the vascular wall is lacking.
Silvio Zaina +3 more
doaj +3 more sources
Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men
Frontiers in Neuroscience, 2021 Epigenetic clocks are among the most promising biomarkers of aging. It is particularly important to establish biomarkers of brain aging to better understand neurodegenerative diseases.
Francine Grodstein +8 more
doaj +1 more source
Scientific Reports, 2023 Age structure information of animal populations is fundamental to their conservation and management. In fisheries, age is routinely obtained by counting daily or annual increments in calcified structures (e.g., otoliths) which requires lethal sampling ...
Benjamin Mayne +11 more
doaj +1 more source
Circadian clocks, epigenetics, and cancer [PDF]
Current Opinion in Oncology, 2015 The interplay between circadian rhythm and cancer has been suggested for more than a decade based on the observations that shift work and cancer incidence are linked. Accumulating evidence implicates the circadian clock in cancer survival and proliferation pathways.
Masri, Selma +2 more
openaire +4 more sources
Epigenetic clock and methylation studies in cats [PDF]
GeroScience, 2021 Abstract Human DNA methylation profiles have been used successfully to develop highly accurate biomarkers of aging (“epigenetic clocks”). Although these human epigenetic clocks are not immediately applicable to all species of the animal kingdom, the principles underpinning them appear to be conserved even in ...
Ken Raj +8 more
openaire +4 more sources
Nature Communications, 2022 The temporal development of tissues and organs may be defined by the genome-wide epigenetic and transcriptional state functioning as the clock. Here the authors found that Fbl, a ribosomal RNA methyltransferase, potentially behaves as a clock during ...
Quan Wu +7 more
doaj +1 more source
, 2022 Background: Epigenetic aging is associated with a plethora of negative health outcomes and increased mortality. Yet, the dynamicity of epigenetic age after exposure to trauma and the factors that influence epigenetic age are not fully understood.
Stringfellow, Rachel +7 more
core +1 more source