Results 21 to 30 of about 35,251 (213)

Epigenetic Clocks and Programmatic Aging

Ageing Research Reviews, 2023
The last decade has seen remarkable progress in the characterization of methylation clocks that track biological age in humans and many other mammalian species. While the biological processes of aging that underlie these clocks have remained unclear, several clues have pointed to a link to developmental mechanisms.
David Gems, Roop Singh Virk, João Pedro de Magalhães   +2 more
openaire   +2 more sources

Circadian clocks, epigenetics, and cancer [PDF]

Current Opinion in Oncology, 2015
The interplay between circadian rhythm and cancer has been suggested for more than a decade based on the observations that shift work and cancer incidence are linked. Accumulating evidence implicates the circadian clock in cancer survival and proliferation pathways.
Masri, Selma, Kinouchi, Kenichiro, Sassone-Corsi, Paolo   +2 more
openaire   +4 more sources

Editorial: Epigenetic Clock: A Novel Tool for Nutrition Studies of Healthy Ageing. [PDF]

J Nutr Health Aging, 2022
He L.
europepmc   +3 more sources

Dynamic epigenetic age mosaicism in the human atherosclerotic artery

PLoS ONE, 2022
Accelerated epigenetic ageing, a promising marker of disease risk, has been detected in peripheral blood cells of atherosclerotic patients, but evidence in the vascular wall is lacking.
Silvio Zaina, Manel Esteller, Isabel Gonçalves, Gertrud Lund   +3 more
doaj   +3 more sources

Cardiovascular health and four epigenetic clocks

Clinical Epigenetics, 2022
Abstract Background Cardiovascular health (CVH) was defined by the American Heart Association as an integrative idealness of seven clinical or lifestyle factors. Based on populations of European ancestry, recent studies have shown that ideal CVH is associated with a slower aging rate. The aging rate is measured by levels
Yun-Hsiang Lo, Wan-Yu Lin
openaire   +2 more sources

Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation

Scientific Reports, 2023
Age structure information of animal populations is fundamental to their conservation and management. In fisheries, age is routinely obtained by counting daily or annual increments in calcified structures (e.g., otoliths) which requires lethal sampling ...
Benjamin Mayne, Tom Espinoza, David A. Crook, Chloe Anderson, Darren Korbie, Jonathan C. Marshall, Mark J. Kennard, Doug J. Harding, Gavin L. Butler, Brien Roberts, Josh Whiley, Sharon Marshall   +11 more
doaj   +1 more source

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936 [PDF]

, 2015
Background: The DNA methylation-based 'epigenetic clock' correlates strongly with chronological age, but it is currently unclear what drives individual differences. We examine cross-sectional and longitudinal associations between the epigenetic clock and
Corley, Janie, Cox, Simon R, Deary, Ian J, Gibson, Jude, Harris, Sarah E, Horvath, Steve, Marioni, Riccardo E, McRae, Allan F, Muniz-Terrera, Graciela, Murphy, Lee, Pattie, Alison, Redmond, Paul, Ritchie, Stuart J, Shah, Sonia, Starr, John M, Taylor, Adele, Visscher, Peter M, Wray, Naomi R   +17 more
core   +1 more source

TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. [PDF]

Nat Aging
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA.   +23 more
europepmc   +3 more sources

Exploring the Relationship of Relative Telomere Length and the Epigenetic Clock in the LipidCardio Cohort [PDF]

, 2019
Telomere length has been accepted widely as a biomarker of aging. Recently, a novel candidate biomarker has been suggested to predict an individual’s chronological age with high accuracy: The epigenetic clock is based on the weighted DNA methylation ...
Banszerus, Verena L., Demuth, Ilja, König, Maximilian, Salewsky, Bastian, Vetter, Valentin M.   +4 more
core   +1 more source

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors. [PDF]

Nat Aging
Fuentealba M, Rouch L, Guyonnet S, Lemaitre JM, de Souto Barreto P, Vellas B, Andrieu S, Furman D.   +7 more
europepmc   +3 more sources