Results 31 to 40 of about 3,274,267 (305)
Efficient Monte Carlo Simulation of Biological Aging
, 1995 A bit-string model of biological life-histories is parallelized, with hundreds of millions of individuals. It gives the desired drastic decay of survival probabilities with increasing age for 32 age intervals.Comment: PostScript file to appear in Int.J ...
Penna, T. J. P., Stauffer, D.
core +1 more source
Neurobiology of Disease, 2005 We have shown that over-expression of human tau (0N3R) in Drosophila larval motor neurons causes significant morphological and functional disruption to the neuromuscular junctions (NMJs).
Francis C. Chee +6 more
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Accelerated aging and psychological age of an individual as risk factors for COVID-19 complications
Наука и инновации в медицине, 2021 Objectives to study the effect of psychological age on the risk of severe forms of Covid-19 in adults. Material and methods. Research method: natural experiment. The 1st measurement: indicators of biopsychological age - mid-2020, the 2nd measurement:
Tatyana N. Berezina +3 more
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A whole lifespan mouse multi-tissue DNA methylation clock
eLife, 2018 Age predictors based on DNA methylation levels at a small set of CpG sites, DNAm clocks, have been developed for humans and extended to several other species.
Margarita V Meer +3 more
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Monte Carlo Simulation of Age-Dependent Host-Parasite Relations
, 2007 The death of a biological population is an extreme event which we investigate here for a host-parasitoid system. Our simulations using the Penna ageing model show how biological evolution can ``teach'' the parasitoids to avoid extinction by waiting for ...
Ana Proykova +7 more
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Current Issues in Molecular BiologyDendritic cells (DCs) are critical antigen-presenting cells that orchestrate the interface between innate and adaptive immunity, making them attractive approaches for cancer immunotherapy.
Mi Eun Kim, Jun Sik Lee
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The Lancet Healthy Longevity, 2023 Biological age is a measure of health that offers insights into ageing. The existing age clocks, although valuable, often trade off accuracy and interpretability. We introduce ExplaiNAble BioLogical Age (ENABL Age), a computational framework that combines machine-learning models with explainable artificial intelligence (XAI) methods to accurately ...
Wei, Qiu +3 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Molecular Foundations of Inflammatory Diseases: Insights into Inflammation and Inflammasomes
Current Issues in Molecular BiologyInflammatory diseases are a global health problem affecting millions of people with a wide range of conditions. These diseases, including inflammatory bowel disease (IBD), rheumatoid arthritis (RA), osteoarthritis (OA), gout, and diabetes, impose a ...
Mi Eun Kim, Jun Sik Lee
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Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source