Results 11 to 20 of about 3,238,552 (285)

Repeated stressors in adulthood increase the rate of biological ageing [PDF]

, 2015
Background Individuals of the same age can differ substantially in the degree to which they have accumulated tissue damage, akin to bodily wear and tear, from past experiences.
Adelman, James S., Costantini, David, Greives, Timothy J., Hau, Michaela, Haussmann, Mark F., Matlack, Christa, Miranda, Ana Catarina, Partecke, Jesko, Quetting, Michael   +8 more
core   +2 more sources

Moral Case for Legal Age Change [PDF]

, 2019
Should a person who feels his legal age does not correspond with his experienced age be allowed to change his legal age? In this paper, I argue that in some cases people should be allowed to change their legal age. Such cases would be when: 1) the person
Räsänen, Joona
core   +1 more source

The temporary cost of dominance

eLife, 2021
In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
Calen P Ryan, Christopher W Kuzawa
doaj   +1 more source

Ageing and cancer: a research gap to fill

Molecular Oncology, 2022
The complex mechanisms of ageing biology are increasingly understood. Interventions to reduce or delay ageing‐associated diseases are emerging. Cancer is one of the diseases promoted by tissue ageing.
Eric Solary, Nancy Abou‐Zeid, Fabien Calvo   +2 more
doaj   +1 more source

GEN-O-MA project: an Italian network studying clinical course and pathogenic pathways of moyamoya disease—study protocol and preliminary results [PDF]

, 2019
Background: GENetics of mOyaMoyA (GEN-O-MA) project is a multicenter observational study implemented in Italy aimed at creating a network of centers involved in moyamoya angiopathy (MA) care and research and at collecting a large series and bio ...
Acerbi, Francesco, Baracchini, Claudio, Bedini, Gloria, Bersano, Anna, Binelli, Simona, Blecharz, Kinga, Bono, Giorgio, Bruzzone, Maria Grazia, Calloni, Maria Vittoria, Capone, Fioravanti, Capra, Valeria, Caputi, Luigi, Caria, Filomena, Carolei, Antonio, Caso, Valeria, Cenzato, Marco, Ciceri, Elisa, Ciusani, Emilio, De Lodovici, Maria Luisa, Dell' Acqua, Maria Luisa, Di Lazzaro, Vincenzo, Di Piero, Vittorio, Esposito, Silvia, Faragò, Giuseppe, Farina, Filippo, Ferroli, Paolo, Franceschetti, Silvana, Fratianni, Alessia, Gioppo, Andrea, Grisoli, Marina, Lanfranconi, Silvia, Lasserve, Elisabeth Tournier, Marzoli, Stefania Bianchi, Nardocci, Nardo, Nava, Sara, null, null, Paciaroni, Maurizio, Pantaleoni, Chiara, Pantoni, Leonardo, Parati, Eugenio Agostino, Pavanello, Marco, Perrone, Patrizia, Pezzini, Alessandro, Prontera, Paolo, Raso, Alessandro, Riva, Daria, Romani, Alfredo, Sacco, Simona, Saletti, Veronica, Sanguigni, Sandro, Sarti, Cristina, Sebastiano, Davide Rossi, Toni, Danilo, Toscano, Massimiliano, Vajkoczy, Peter, Zedde, Maria Luisa, Zibordi, Federica, Zini, Andrea   +57 more
core   +1 more source

Crystal Structure of the N112A Mutant of the Light-Driven Sodium Pump KR2

Crystals, 2020
The light-driven sodium pump KR2, found in 2013 in the marine bacteria Krokinobacter eikastus, serves as a model protein for the studies of the sodium-pumping microbial rhodopsins (NaRs). KR2 possesses a unique NDQ (N112, D116, and Q123) set of the amino
Nina Maliar, Kirill Kovalev, Christian Baeken, Taras Balandin, Roman Astashkin, Maksim Rulev, Alexey Alekseev, Nikolay Ilyinsky, Andrey Rogachev, Vladimir Chupin, Dmitry Dolgikh, Mikhail Kirpichnikov, Valentin Gordeliy   +12 more
doaj   +1 more source

Biological vascular age and its relationship with cardiovascular risk factors

Кардиоваскулярная терапия и профилактика, 2022
Aim. To study of the relationship between cardiovascular risk factors and biological vascular age.Material and methods. The biological vascular age was estimated using models based on the arterial wall parameters.
A. A. Akopyan, I. D. Strazhesko, V. G. Klyashtorny, I. A. Orlova   +3 more
doaj   +1 more source

Age Prediction in Healthy Subjects Using RR Intervals and Heart Rate Variability: A Pilot Study Based on Deep Learning

Applied Sciences, 2023
Autonomic cardiac regulation is affected by advancing age and can be observed by variations in R-peak to R-peak intervals (RRIs). Heart rate variability (HRV) has been investigated as a physiological marker for predicting age using machine learning ...
Kyung Hyun Lee, Sangwon Byun
doaj   +1 more source

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease [PDF]

, 2013
Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length as ...
Barclay, Stephen, McGuinness, Dagmara, McLauchlan, John, Mills, Peter R., Patel, Arvind H., Robinson, Mark W., Shiels, Paul G., Swann, Rachael   +7 more
core   +2 more sources

Viral rhodopsins 1 are an unique family of light-gated cation channels

Nature Communications, 2020
Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of ...
Dmitrii Zabelskii, Alexey Alekseev, Kirill Kovalev, Vladan Rankovic, Taras Balandin, Dmytro Soloviov, Dmitry Bratanov, Ekaterina Savelyeva, Elizaveta Podolyak, Dmytro Volkov, Svetlana Vaganova, Roman Astashkin, Igor Chizhov, Natalia Yutin, Maksim Rulev, Alexander Popov, Ana-Sofia Eria-Oliveira, Tatiana Rokitskaya, Thomas Mager, Yuri Antonenko, Riccardo Rosselli, Grigoriy Armeev, Konstantin Shaitan, Michel Vivaudou, Georg Büldt, Andrey Rogachev, Francisco Rodriguez-Valera, Mikhail Kirpichnikov, Tobias Moser, Andreas Offenhäusser, Dieter Willbold, Eugene Koonin, Ernst Bamberg, Valentin Gordeliy   +33 more
doaj   +1 more source