Results 231 to 240 of about 3,274,267 (305)

Social determinants of health and biological age among diverse U.S. Adults, NHANES 2011-2018. [PDF]

BMC Public Health
Mesa RA, Llabre MM, Lee DJ, Rundek T, Kezios KL, Al Hazzouri AZ, Elfassy T.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The mediating role of biological age in the impact of mood instability symptoms on neurodegenerative disease and mortality. [PDF]

BMC Med
Wang J, Zhang J, Liu K, Wang J, Wang Y, Ma X, Li Z, He S, Liu X, Chen P, Li J.   +10 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Plasma proteomic Alzheimer's risk score: Biological age clock and pseudotime trajectory. [PDF]

Alzheimers Dement
Liu S, Huang YN, Park T, Lee EH, Chaudhuri S, Adzibolosu N, Bice PJ, Dage JL, Brosch JR, Gao S, Apostolova LG, Wilcock DM, Risacher SL, Saykin AJ, Nho K.   +14 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A Machine-Learning Model of Chronological Age Based on Routine Blood Biomarkers in a Central European Population: A Potential Biological Age Marker. [PDF]

J Aging Res
Borsky P, Holmannova D, Maresova T, Cizkova A, Kempfova T, Byma S, Philipp T, Borska L.   +7 more
europepmc   +1 more source

The association between dietary iron intake and the incidence of cardiometabolic multimorbidity: the mediating role of biological age. [PDF]

BMC Public Health
Chen N, Yang D, Qiao G, Ke Z, Tang Y, Zhou J, Zhu X.   +6 more
europepmc   +1 more source