Results 71 to 80 of about 3,406,662 (333)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]

open access: yes, 2008
Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C., Michael S C Thomas
core  

Time flies : autophagy during ageing in Drosophila [PDF]

open access: yes, 2013
The process of ageing compromises the age-associated decrease in fertility, gradual loss of function, and increased vulnerability to disease, which progressively diminishes the capability of an organism to survive [1-3]. Unsurprisingly, in the past years
Nezis, I. P.   +5 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

HEART AND AGE (PART I): AGEING THEORIES AND MORPHOLOGICAL CHANGES

open access: yesКардиоваскулярная терапия и профилактика, 2013
Heart ageing is a complex process including multiple cellular and molecular-level changes and resulting in different ageing phenotypes within the same biological species.
D. U. Akasheva   +4 more
doaj   +1 more source

Theories of biological aging

open access: yesExperimental Gerontology, 1985
Experimental Gerontology 20 (1985) 145-159. doi:10.1016/0531-5565(85)90032-4 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:36 ; DOI:10.1016/0531-5565(85)90032-4 ; Page Range: 145 ...
Center for Gerontological Studies, University of Florida 3357 GPA, Gaineville, Florida 32611 USA ( host institution )   +1 more
openaire   +3 more sources

ExplaiNAble BioLogical Age (ENABL Age): an artificial intelligence framework for interpretable biological age

open access: yesThe Lancet Healthy Longevity, 2023
Biological age is a measure of health that offers insights into ageing. The existing age clocks, although valuable, often trade off accuracy and interpretability. We introduce ExplaiNAble BioLogical Age (ENABL Age), a computational framework that combines machine-learning models with explainable artificial intelligence (XAI) methods to accurately ...
Wei, Qiu   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Incident disability in older adults: prediction models based on two British prospective cohort studies

open access: yes, 2014
Objective: to develop and validate a prediction model for incident locomotor disability after 7 years in older adults.Setting: prospective British cohort studies: British Women's Heart and Health Study (BWHHS) for development and the English Longitudinal
Bowling, A.   +15 more
core   +1 more source

Prevention of dementia in an ageing world : Evidence and biological rationale

open access: yes, 2020
As the population ages, the number of people with dementia is expected to increase in the coming decades, with consequences at the societal and individual levels.
Grande, Giulia,   +2 more
core   +1 more source

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