Results 111 to 120 of about 911,648 (354)

Biological Clocks as Age Estimation Markers in Animals: From Teeth to DNA, a Review and Meta-analysis (Dataset)

, 2022
Louis‐Stéphane Le Clercq, Antoinette Kotzé, J. Paul Grobler, Desiré L. Dalton   +3 more
openalex   +2 more sources

Treatment with Bacterial Biologics Promotes Healthy Aging and Traumatic Brain Injury Responses in Adult Drosophila, Modeling the Gut–Brain Axis and Inflammation Responses [PDF]

, 2021
Brandon Molina, Jessica Mastroianni, Ema Suarez, Brijinder Soni, Erica M. Forsberg, Kim D. Finley   +5 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

An In Silico Model to Simulate the Evolution of Biological Aging

, 2016
Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population dynamics, and the ...
Valenzano, Dario Riccardo, Šajina, Arian   +1 more
core   +1 more source

The NHANES Biological Age Index demonstrates accelerated aging in MS patients [PDF]

, 2023
Annalise E. Miner, Jennifer H. Yang, Revere P. Kinkel, Jennifer Graves   +3 more
openalex   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Influence of Maternal Inflammatory Status on Fetal Telomere Length at Birth

Biomedicines
Background/Objectives: Fetal telomere length (FTL) at birth is considered a key marker of early biological aging and future disease risk. While chronic inflammation is known to accelerate telomere attrition in adults, limited evidence exists on how ...
Mircea Diaconu, Flavius Olaru, Ahmed Abu-Awwad, Simona-Alina Abu-Awwad, Tiberiu Dragomir, Geanina Sacarin, Nicolae Ciprian Pilut, Bogdan Sorop, Melisa Bicu, Razvan Nitu   +9 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Association of Higher Dietary Omega‐3 Fatty Acid Intake With Cardiovascular‐Kidney‐Metabolic Syndrome Stage Severity and Mortality in US Adults: A Cross‐Sectional and Prospective Cohort Analysis of NHANES 1999 to 2018

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiovascular‐kidney‐metabolic (CKM) syndrome interlinks obesity, diabetes, kidney disease, and cardiovascular dysfunction. Omega‐3 polyunsaturated fatty acids (n‐3 PUFAs) possess anti‐inflammatory and metabolic properties potentially ...
Li‐Ling Zhang, Xian‐Guan Zhu, Jing Chen, Pei Nie, Jing‐Cheng Shi, Zhen Zhang, Yuan‐Xi Zheng, Rui Qiao, Liang‐Chuan Chen   +8 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source