Availability and reimbursement of biological products for severe asthma in Bulgaria
SAGE Open Medicine, 2020 Objectives: This study aims to analyze the reimbursement and cost of biological therapy for severe asthma in Bulgaria during 2014–2019 from the perspective of the National Health Insurance Fund.
Petya Milushewa +2 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens [PDF]
, 2000 The rate of expansion of bacterial colonies of S. liquefaciens is investigated in terms of a mathematical model that combines biological as well as hydrodynamic processes. The relative importance of cell differentiation and production of an extracellular
Andresen, P. +3 more
core +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Assessing the role of dispersed floralresources for managed bees in providingsupporting ecosystem services for croppollination [PDF]
, 2018 Most pollination ecosystem services studies have focussed on wild pollinators and their dependence on natural floral resources adjacent to crop fields. However, managed pollinators depend on a mixture of floral resources that are spatially separated from
Colville, Jonathan F. +4 more
core +2 more sources
Gene expression profile change and associated physiological and pathological effects in mouse liver induced by fasting and refeeding. [PDF]
PLoS ONE, 2011 Food availability regulates basal metabolism and progression of many diseases, and liver plays an important role in these processes. The effects of food availability on digital gene expression profile, physiological and pathological functions in liver ...
Fang Zhang +4 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Navigating multiple sources of healing in the context of HIV/AIDS and wide availability of antiretroviral treatment: a qualitative study of community participants’ perceptions and experiences in rural South Africa [PDF]
, 2018 Background: South Africa introduced the world’s largest antiretroviral treatment (ART) program in 2004 and since 2016 the Department of Health implemented a universal Treatment as Prevention (TasP) strategy.
Moshabela, Mosa +3 more
core +1 more source
Deficiencia de zinc y sus implicaciones funcionales Zinc deficiency and its functional implications
Salud Pública de México, 1998 El presente trabajo tiene por objeto revisar los aspectos teóricos y los estudios realizados en México que sugieren la existencia de la deficiencia moderada de zinc en niños de población rural, así como algunas de las consecuencias de dicha deficiencia ...
JORGE L ROSADO
doaj
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source