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Biological clocks in theory and experiments [PDF]
Eukaryotes and some prokaryotes have adapted to the 24 h day/night cycle by evolving circadian clocks. The circadian clock now controls 24-hour rhythms in very many aspects of metabolism, physiology and behaviour. Day-length (photoperiod) measurement depends on the circadian clock, so the 24 h clock mechanism also governs seasonal rhythms, such as ...
Millar Andrew J
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Biological clocks: riding the tides. [PDF]
Animals with habitats in the intertidal zone often display biological rhythms that coordinate with both the tidal and the daily environmental cycles. Two recent studies show that the molecular components of the biological clocks mediating tidal rhythms are likely different from the phylogenetically conserved components that mediate circadian (daily ...
de la Iglesia HO, Johnson CH.
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Slowing down decay: biological clocks in personalized medicine [PDF]
This article discusses so-called biological clocks. These technologies, based on aging biomarkers, trace and measure molecular changes in order to monitor individuals' “true” biological age against their chronological age. Drawing on the concept of decay,
Clémence Pinel+2 more
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An integrative study of five biological clocks in somatic and mental health [PDF]
Biological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illness and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and
Rick Jansen+6 more
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Biological switches and clocks [PDF]
To introduce this special issue on biological switches and clocks, we review the historical development of mathematical models of bistability and oscillations in chemical reaction networks. In the 1960s and 1970s, these models were limited to well-studied biochemical examples, such as glycolytic oscillations and cyclic AMP signalling.
John J. Tyson+4 more
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How to Synchronize Biological Clocks [PDF]
This paper is concerned with a novel algorithm to study networks of biological clocks. A new set of conditions is established that can be used to verify whether an existing network synchronizes or to give guidelines to construct a new synthetic network of biological oscillators that synchronize.
Giovanni Russo, Mario di Bernardo
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Biological clocks: their relevance to immune-allergic diseases [PDF]
The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the past 15 years on the genetic and molecular mechanisms regulating many physiological functions, has renewed the attention to the importance of circadian rhythms ...
Roberto Paganelli+2 more
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Biological clock: Biological clocks may modulate drug addiction [PDF]
A recent study by McClung's group (2005),1 expanding on an earlier report,2 provides mechanistic insight to the timekeeper gene, Clock, which may regulate dopaminergic transmission and cocaine reward. This work provides further evidence that cocaine-induced effects have circadian influences.
Vadim Yuferov+2 more
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Biological clocks and the digestive system [PDF]
Circadian rhythms play a major role in regulating the digestive systems of many organisms. Cell proliferation, migration, differentiation, and even structure vary as a function of time of day in many different digestive organs (i.e., stomach, gut, liver, and pancreas) and cell types, resulting in regionally specific temporal variations in protein and ...
Lawrence A. Scheving
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Biological Clocks and Rhythms of Anger and Aggression [PDF]
The body’s internal timekeeping system is an under-recognized but highly influential force in behaviors and emotions including anger and reactive aggression. Predictable cycles or rhythms in behavior are expressed on several different time scales such as
Suzanne Hood, Shimon Amir
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