Results 11 to 20 of about 5,783,416 (253)
Slowing down decay: biological clocks in personalized medicine
Frontiers in Sociology, 2023 This article discusses so-called biological clocks. These technologies, based on aging biomarkers, trace and measure molecular changes in order to monitor individuals' “true” biological age against their chronological age. Drawing on the concept of decay,
Clémence Pinel +2 more
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An integrative study of five biological clocks in somatic and mental health
eLife, 2021 Biological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illness and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and
Rick Jansen +6 more
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Biological clocks as age estimation markers in animals: a systematic review and meta‐analysis
Biological Reviews, 2023 Various biological attributes associated with individual fitness in animals change predictably over the lifespan of an organism. Therefore, the study of animal ecology and the work of conservationists frequently relies upon the ability to assign animals ...
Desire Lee +2 more
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Biological clocks and incremental growth line formation in dentine
Journal of Anatomy, 2020 Dentine‐ and enamel‐forming cells secrete matrix in consistent rhythmic phases, resulting in the formation of successive microscopic growth lines inside tooth crowns and roots. Experimental studies of various mammals have proven that these lines are laid
Amanda M. Papakyrikos +10 more
semanticscholar +2 more sources
Aging Cell, 2021 Epigenetic alterations are a hallmark of aging and age‐related diseases. Computational models using DNA methylation data can create “epigenetic clocks” which are proposed to reflect “biological” aging. Thus, it is important to understand the relationship
Willard Freeman +2 more
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Decelerating ageing and biological clocks by autophagy
Nature Reviews Molecular Cell Biology, 2019 Ageing is the most important risk factor for the majority of human pathologies. We propose the concept that the advancement of the hallmarks of ageing is dictated by several distinct biological clocks that can be decelerated by the induction of autophagy.
Carlos Lopez-Otin, Guido Kroemer
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Computing with biological switches and clocks [PDF]
Natural Computing, 2018 The complex dynamics of biological systems is primarily driven by molecular interactions that underpin the regulatory networks of cells. These networks typically contain positive and negative feedback loops, which are responsible for switch-like and ...
Neil Dalchau +6 more
semanticscholar +3 more sources
Biological Clocks: Riding the Tides [PDF]
Current Biology, 2013 Animals with habitats in the intertidal zone often display biological rhythms that coordinate with both the tidal and the daily environmental cycles. Two recent studies show that the molecular components of the biological clocks mediating tidal rhythms ...
H. O. de la Iglesia, C. Johnson
semanticscholar +2 more sources
Biological Clocks and Rhythms of Anger and Aggression
Frontiers in Behavioral Neuroscience, 2018 The body’s internal timekeeping system is an under-recognized but highly influential force in behaviors and emotions including anger and reactive aggression. Predictable cycles or rhythms in behavior are expressed on several different time scales such as
Suzanne Hood, Shimon Amir
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Decoding aging clocks: New insights from metabolomics
Cell MetabolismChronological age is a crucial risk factor for diseases and disabilities among older adults. However, individuals of the same chronological age often exhibit divergent biological aging states, resulting in distinct individual risk profiles. Chronological
Brian Kennedy, Evelyne Bischof
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