Results 31 to 40 of about 5,783,416 (253)

Multi-Modal Regulation of Circadian Physiology by Interactive Features of Biological Clocks

Biology, 2021
Simple Summary Circadian rhythms, driven by molecular clockwork, exist in nearly all cells and tissues throughout the body, and these rhythmic oscillators constitute tightly coupled network systems that generate rhythmic physiology and behavior.
Yool Lee, J. Wisor
semanticscholar   +1 more source

Assessing the Causal Association between Biological Aging Biomarkers and the Development of Cerebral Small Vessel Disease: A Mendelian Randomization Study

Biology, 2023
Biological aging biomarkers, such as leukocyte telomere length (LTL) and epigenetic clocks, have been associated with the risk of cerebral small vessel disease (CSVD) in several observational studies.
Biying Lin, Yuzhu Mu, Zhongxiang Ding
doaj   +1 more source

Acknowledgment to Reviewers of Clocks & Sleep in 2020

, 2021
The peer review process represents the driving force of journal development, with reviewers acting as the gatekeepers who ensure that Clocks & Sleep maintains its high-quality standard of published papers [...
Sleep Editorial Office, Sleep Editorial Office Clocks &, Clocks &   +2 more
core   +1 more source

Evaluation of pediatric epigenetic clocks across multiple tissues

Clinical Epigenetics, 2023
Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang, Linran Zhou, Wei Perng, Carmen J. Marsit, Anna K. Knight, Andres Cardenas, Max T. Aung, Marie-France Hivert, Izzuddin M. Aris, Jaclyn M. Goodrich, Alicia K. Smith, Abigail Gaylord, Rebecca C. Fry, Emily Oken, George O’Connor, Douglas M. Ruden, Leonardo Trasande, Julie B. Herbstman, Carlos A. Camargo, Nicole R. Bush, Anne L. Dunlop, Dana M. Dabelea, Margaret R. Karagas, Carrie V. Breton, Carole Ober, Todd M. Everson, Grier P. Page, Christine Ladd-Acosta, on behalf of program collaborators for Environmental influences on Child Health Outcomes   +28 more
doaj   +1 more source

Balance equations can buffer noisy and sustained environmental perturbations of circadian clocks [PDF]

, 2010
We present a new approach to understanding how regulatory networks such as circadian clocks might evolve robustness to environmental fluctuations. The approach is in terms of new balance equations that we derive.
David A. Rand, Domijan, Mirela, Rand, D. A. (David A.), Mirela Domijan   +3 more
core   +1 more source

Macrophage Meets the Circadian Clock: Implication of the Circadian Clock in the Role of Macrophages in Acute Lower Respiratory Tract Infection

Frontiers in Cellular and Infection Microbiology, 2022
The circadian rhythm is a biological system that creates daily variations of physiology and behavior with a 24-h cycle, which is precisely controlled by the molecular circadian clock.
Ken Shirato, Shogo Sato
doaj   +1 more source

Synchronization of clocks [PDF]

, 2012
Peer ...
Czolczynski, Krzysztof, Kapitaniak, Marcin, Kapitaniak, Tomasz, Perlikowski, Przemyslaw, Stefanski, Andrzej   +4 more
core   +1 more source

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

bioRxiv, 2021
Biological age (BA), a measure of functional capacity and prognostic of health outcomes that discriminates between individuals of the same chronological age (chronAge), has been estimated using a variety of biomarkers.
E. Macdonald-Dunlop, N. Taba, L. Klarić, Azra Frkatović, R. Walker, C. Hayward, T. Esko, C. Haley, K. Fischer, James F. Wilson, Peter K. Joshi   +10 more
semanticscholar   +1 more source

Bayesian neural networks for the optimisation of biological clocks in humans

bioRxiv, 2020
DNA methylation is related to aging. Some researchers, such as Horvath or Levine have managed to create epigenetic and biological clocks that predict chronological age using methylation data.
Gerardo Alfonso, J. González
semanticscholar   +1 more source

Robustness from flexibility in the fungal circadian clock [PDF]

, 2010
Background Robustness is a central property of living systems, enabling function to be maintained against environmental perturbations. A key challenge is to identify the structures in biological circuits that confer system-level properties such as ...
Andrew J Millar, Paul E Brown, David A Rand, Akman, Ozgur E., Rand, D. A. (David A.), Akman, Ozgur E, Brown, Paul E, Rand, David A., Ozgur E Akman, Millar, Andrew J; id_orcid, Brown, Paul E., Millar, A. J. (Andrew J.), Millar, Andrew J., Rand, David A   +13 more
core   +1 more source