Results 51 to 60 of about 5,783,416 (253)

Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial

Nature Aging
While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking.
H. Bischoff-Ferrari, S. Gaengler, Maud Wieczorek, D. Belsky, Joanne Ryan, R. Kressig, H. B. Stähelin, R. Theiler, B. Dawson-Hughes, René Rizzoli, B. Vellas, L. Rouch, S. Guyonnet, A. Egli, E. Orav, Walter C. Willett, S. Horvath   +16 more
semanticscholar   +1 more source

Organ-specific biological clocks: ageotyping for personalized anti-aging medicine.

Ageing Research Reviews
Aging is a complex multidimensional, progressive remodeling process affecting multiple organ systems. While many studies have focused on studying aging across multiple organs, assessment of the contribution of individual organs to overall aging processes
F. Prattichizzo, Chiara Frigé, Valeria Pellegrini, L. Scisciola, A. Santoro, D. Monti, M. R. Rippo, M. Ivanchenko, Fabiola Olivieri, Claudio Franceschi   +9 more
semanticscholar   +1 more source

Intrinsic Clocks

, 2018
"Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as
Partonen, Timo, Daniela D. Pollak, Timo Partonen, Pollak, Daniela D.   +3 more
core   +1 more source

Making time: conservation of biological clocks from fungi to animals

Microbiology spectrum, 2017
The capacity for biological timekeeping arose at least three times through evolution, in prokaryotic cyanobacteria, in cells that evolved into higher plants, and within the group of organisms that eventually became the fungi and the animals.
J. Dunlap, J. Loros
semanticscholar   +1 more source

Loss of functional cryptochrome 1 reduces robustness of 24-hour behavioral rhythms in monarch butterflies

iScience
Summary: Light is one of the strongest cues for entrainment of circadian clocks. While some insect species rely only on visual input, others like Drosophila melanogaster use both the visual system and the deep-brain blue-light photoreceptor cryptochrome ...
Samantha E. Iiams, Guijun Wan, Jiwei Zhang, Aldrin B. Lugena, Ying Zhang, Ashley N. Hayden, Christine Merlin   +6 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity

Cell Reports
Summary: Ribosome composition is dynamic, shifting with cell state and stress, but whether it varies with circadian time is unknown. Here, we uncover circadian clock-driven changes in ribosome composition in Neurospora crassa.
Teresa M. Lamb, Kathrina D. Castillo, Rachel Porter, Cheng Wu, Samuel O. Purvine, Griffin Best, Erika Zink, Ebimobowei O. Preh, Lunda Shen, Matthew S. Sachs, Deborah Bell-Pedersen   +10 more
doaj   +1 more source

Epigenetic age acceleration in surviving versus deceased COVID-19 patients with acute respiratory distress syndrome following hospitalization

Clinical Epigenetics, 2023
Background Aging has been reported as a major risk factor for severe symptoms and higher mortality rates in COVID-19 patients. Molecular hallmarks such as epigenetic alterations and telomere attenuation reflect the biological process of aging. Epigenetic
Yosra Bejaoui, Fathima Humaira Amanullah, Mohamad Saad, Sara Taleb, Martina Bradic, Andre Megarbane, Ali Ait Hssain, Charbel Abi Khalil, Nady El Hajj   +8 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source