Results 61 to 70 of about 72,064 (292)
Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]
, 2017 The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana +3 more
core +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada +6 more
wiley +1 more source
Critical review of aging clocks and factors that may influence the pace of aging
Frontiers in AgingBackground and objectivesAging clocks are computational models designed to measure biological age and aging rate based on age-related markers including epigenetic, proteomic, and immunomic changes, gut and skin microbiota, among others. In this narrative
Mildred Min +12 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Life, The Universe, and Nothing: Life and Death in an Ever-Expanding Universe [PDF]
, 1999 Current evidence suggests that the cosmological constant is not zero, or that we live in an open universe. We examine the implications for the future under these assumptions, and find that they are striking.
Krauss, Lawrence M., Starkman, Glenn D.
core +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Assessing the utility of epigenetic clocks for health prediction in South Korean
Frontiers in AgingEpigenetic clocks have been developed to track both chronological age and biological age, which is defined by physiological biomarkers and the risk of adverse health outcomes.
Dong Jun Kim +6 more
doaj +1 more source
DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan
Neuroscience Insights, 2020 The number of age predictors based on DNA methylation (DNAm) profile is rising due to their potential in predicting healthspan and application in age-related illnesses, such as neurodegenerative diseases.
Tessa Bergsma, Ekaterina Rogaeva
doaj +1 more source
Dynamical fluctuations in biochemical reactions and cycles [PDF]
, 2010 We develop theory for the dynamics and fluctuations in some cyclic and linear biochemical reactions. We use the approach of maximum caliber, which computes the ensemble of paths taken by the system, given a few experimental observables. This approach may
Dill, K. A. +3 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source