Results 21 to 30 of about 2,986,080 (351)

Biological clocks as age estimation markers in animals: a systematic review and meta‐analysis

Biological Reviews of The Cambridge Philosophical Society, 2023
Various biological attributes associated with individual fitness in animals change predictably over the lifespan of an organism. Therefore, the study of animal ecology and the work of conservationists frequently relies upon the ability to assign animals ...
Louis-Stéphane Le Clercq, A. Kotzé, J. Grobler, D. Dalton   +3 more
semanticscholar   +1 more source

Crosstalk between vrille transcripts, proteins, and regulatory elements controlling circadian rhythms and development in Drosophila

iScience, 2021
Summary: The vrille (vri) gene encodes a transcriptional repressor required for Drosophila development as well as circadian behavior in adults. Alternate first exons produce vri transcripts predicted to produce a short VRI isoform during development and ...
Kushan L. Gunawardhana, Gustavo B.S. Rivas, Courtney Caster, Paul E. Hardin   +3 more
doaj   +1 more source

Cryptochrome 1 mediates light-dependent inclination magnetosensing in monarch butterflies

Nature Communications, 2021
Exactly how some animals use magnetic fields to navigate is a longstanding puzzle. A study using a new behavioural assay and transgenic butterflies finds the cryptochrome gene necessary for inclination-based magnetic sensing, and shows that both antennae
Guijun Wan, Ashley N. Hayden, Samantha E. Iiams, Christine Merlin   +3 more
doaj   +1 more source

Assessing the Causal Association between Biological Aging Biomarkers and the Development of Cerebral Small Vessel Disease: A Mendelian Randomization Study

Biology, 2023
Biological aging biomarkers, such as leukocyte telomere length (LTL) and epigenetic clocks, have been associated with the risk of cerebral small vessel disease (CSVD) in several observational studies.
Biying Lin, Yuzhu Mu, Zhongxiang Ding
doaj   +1 more source

Evaluation of pediatric epigenetic clocks across multiple tissues

Clinical Epigenetics, 2023
Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang, Linran Zhou, Wei Perng, Carmen J. Marsit, Anna K. Knight, Andres Cardenas, Max T. Aung, Marie-France Hivert, Izzuddin M. Aris, Jaclyn M. Goodrich, Alicia K. Smith, Abigail Gaylord, Rebecca C. Fry, Emily Oken, George O’Connor, Douglas M. Ruden, Leonardo Trasande, Julie B. Herbstman, Carlos A. Camargo, Nicole R. Bush, Anne L. Dunlop, Dana M. Dabelea, Margaret R. Karagas, Carrie V. Breton, Carole Ober, Todd M. Everson, Grier P. Page, Christine Ladd-Acosta, on behalf of program collaborators for Environmental influences on Child Health Outcomes   +28 more
doaj   +1 more source

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

bioRxiv, 2021
Biological age (BA), a measure of functional capacity and prognostic of health outcomes that discriminates between individuals of the same chronological age (chronAge), has been estimated using a variety of biomarkers.
E. Macdonald-Dunlop, N. Taba, L. Klarić, Azra Frkatović, R. Walker, C. Hayward, T. Esko, C. Haley, K. Fischer, James F. Wilson, Peter K. Joshi   +10 more
semanticscholar   +1 more source

Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging

Aging Cell, 2021
Epigenetic alterations are a hallmark of aging and age‐related diseases. Computational models using DNA methylation data can create “epigenetic clocks” which are proposed to reflect “biological” aging. Thus, it is important to understand the relationship
Hunter L Porter, Chase A. Brown, Xiavan Roopnarinesingh, Cory B. Giles, Constantin Georgescu, W. Freeman, J. Wren   +6 more
semanticscholar   +1 more source

Macrophage Meets the Circadian Clock: Implication of the Circadian Clock in the Role of Macrophages in Acute Lower Respiratory Tract Infection

Frontiers in Cellular and Infection Microbiology, 2022
The circadian rhythm is a biological system that creates daily variations of physiology and behavior with a 24-h cycle, which is precisely controlled by the molecular circadian clock.
Ken Shirato, Shogo Sato
doaj   +1 more source

Rhythms of Locomotion Expressed by Limulus polyphemus, the American Horseshoe Crab: II. Relationship to Circadian Rhythms of Visual Sensitivity [PDF]

, 2008
In the laboratory, horseshoe crabs express a circadian rhythm of visual sensitivity as well as daily and circatidal rhythms of locomotion. The major goal of this investigation was to determine whether the circadian clock underlying changes in visual ...
Bedford, Lisa, Chabot, Christopher C., Watson, Winsor H., III   +2 more
core   +3 more sources

Biological clocks and incremental growth line formation in dentine

Journal of Anatomy, 2020
Dentine‐ and enamel‐forming cells secrete matrix in consistent rhythmic phases, resulting in the formation of successive microscopic growth lines inside tooth crowns and roots. Experimental studies of various mammals have proven that these lines are laid
Amanda M. Papakyrikos, M. Arora, C. Austin, J. Boughner, T. Capellini, H. L. Dingwall, Quentin Greba, J. Howland, Akiko Kato, Xiu-Ping Wang, Tanya M. Smith   +10 more
semanticscholar   +1 more source