Results 31 to 40 of about 2,986,080 (351)
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. [PDF]
, 2019 MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy.
Agard, Bruno +42 more
core +3 more sources
Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
, 2017 Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core +2 more sources
Reciprocity Between Robustness of Period and Plasticity of Phase in Biological Clocks. [PDF]
Physical Review Letters, 2015 Circadian clocks exhibit the robustness of period and plasticity of phase against environmental changes such as temperature and nutrient conditions. Thus far, however, it is unclear how both are simultaneously achieved.
Tetsuhiro S. Hatakeyama, K. Kaneko
semanticscholar +1 more source
Formal Systems Architectures for Biology [PDF]
, 2011 When the word "systems" is used in systems biology, it invokes a variety of assumptions about what defines the subject under investigation, which in turn can lead to divergent research outcomes.
Bradly Alicea
core +2 more sources
Towards Cancer Theory – Circadian and 11-Day Biological Clocks [PDF]
Middle East Journal of Cancer, 2021 Background: In the current study, we used the information-hierarchical system approach to examine human metabolism. Metabolism hierarchical structure, beginning from enzyme level, is controlled by the established information principle and divine section ...
Yuri Kirsta, Dmitry Kirsta
doaj +1 more source
Circadian Gating of the Cell Cycle Revealed in Single Cyanobacterial Cells [PDF]
, 2009 Although major progress has been made in uncovering the machinery that underlies individual biological clocks, much less is known about how multiple clocks coordinate their oscillations. We simultaneously tracked cell division events and circadian phases
Dong, Guogang +4 more
core +1 more source
Epigenetics, 2022 Epigenetic clocks quantify regular changes in DNA methylation that occur with age, or in relation to biomarkers of ageing, and are strong predictors of morbidity and mortality.
Christopher W. Kuzawa +9 more
doaj +1 more source
New Insights Into Cancer Chronotherapies
Frontiers in Pharmacology, 2021 Circadian clocks participate in the coordination of various metabolic and biological activities to maintain homeostasis. Disturbances in the circadian rhythm and cancers are closely related.
Jingxuan Zhou +10 more
doaj +1 more source
Decelerating ageing and biological clocks by autophagy
Nature reviews. Molecular cell biology, 2019 Ageing is the most important risk factor for the majority of human pathologies. We propose the concept that the advancement of the hallmarks of ageing is dictated by several distinct biological clocks that can be decelerated by the induction of autophagy.
C. López-Otín, G. Kroemer
semanticscholar +1 more source
Novel Epigenetic Clock Biomarkers of Age-Related Macular Degeneration
Frontiers in Medicine, 2022 Age-Related Macular Degeneration (AMD) is a bilateral ocular condition resulting in irreversible vision impairment caused by the progressive loss of photoreceptors in the macula, a region at the center of the retina. The progressive loss of photoreceptor
Saurav Mallik +5 more
doaj +1 more source