Results 31 to 40 of about 69,526 (310)
Towards Cancer Theory – Circadian and 11-Day Biological Clocks [PDF]
Middle East Journal of Cancer, 2021 Background: In the current study, we used the information-hierarchical system approach to examine human metabolism. Metabolism hierarchical structure, beginning from enzyme level, is controlled by the established information principle and divine section ...
Yuri Kirsta, Dmitry Kirsta
doaj +1 more source
Rhythms of Locomotion Expressed by Limulus polyphemus, the American Horseshoe Crab: II. Relationship to Circadian Rhythms of Visual Sensitivity [PDF]
, 2008 In the laboratory, horseshoe crabs express a circadian rhythm of visual sensitivity as well as daily and circatidal rhythms of locomotion. The major goal of this investigation was to determine whether the circadian clock underlying changes in visual ...
Bedford, Lisa +2 more
core +3 more sources
New Insights Into Cancer Chronotherapies
Frontiers in Pharmacology, 2021 Circadian clocks participate in the coordination of various metabolic and biological activities to maintain homeostasis. Disturbances in the circadian rhythm and cancers are closely related.
Jingxuan Zhou +10 more
doaj +1 more source
Computing with biological switches and clocks [PDF]
Natural Computing, 2018 The complex dynamics of biological systems is primarily driven by molecular interactions that underpin the regulatory networks of cells. These networks typically contain positive and negative feedback loops, which are responsible for switch-like and oscillatory dynamics, respectively.
Andrew Phillips +8 more
openaire +5 more sources
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. [PDF]
, 2019 MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy.
Agard, Bruno +42 more
core +3 more sources
Novel Epigenetic Clock Biomarkers of Age-Related Macular Degeneration
Frontiers in Medicine, 2022 Age-Related Macular Degeneration (AMD) is a bilateral ocular condition resulting in irreversible vision impairment caused by the progressive loss of photoreceptors in the macula, a region at the center of the retina. The progressive loss of photoreceptor
Saurav Mallik +5 more
doaj +1 more source
Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
, 2017 Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core +2 more sources
Epigenetics, 2022 Epigenetic clocks quantify regular changes in DNA methylation that occur with age, or in relation to biomarkers of ageing, and are strong predictors of morbidity and mortality.
Christopher W. Kuzawa +9 more
doaj +1 more source
Circadian Gating of the Cell Cycle Revealed in Single Cyanobacterial Cells [PDF]
, 2009 Although major progress has been made in uncovering the machinery that underlies individual biological clocks, much less is known about how multiple clocks coordinate their oscillations. We simultaneously tracked cell division events and circadian phases
Dong, Guogang +4 more
core +1 more source
Distinguishable DNA methylation defines a cardiac-specific epigenetic clock
Clinical Epigenetics, 2023 Background The present study investigates whether epigenetic differences emerge in the heart of patients undergoing cardiac surgery for an aortic valvular replacement (AVR) or coronary artery bypass graft (CABG).
A. Mongelli +20 more
doaj +1 more source