Results 51 to 60 of about 2,986,080 (351)

Epigenetic age acceleration in surviving versus deceased COVID-19 patients with acute respiratory distress syndrome following hospitalization

Clinical Epigenetics, 2023
Background Aging has been reported as a major risk factor for severe symptoms and higher mortality rates in COVID-19 patients. Molecular hallmarks such as epigenetic alterations and telomere attenuation reflect the biological process of aging. Epigenetic
Yosra Bejaoui, Fathima Humaira Amanullah, Mohamad Saad, Sara Taleb, Martina Bradic, Andre Megarbane, Ali Ait Hssain, Charbel Abi Khalil, Nady El Hajj   +8 more
doaj   +1 more source

Biological clock: Biological clocks may modulate drug addiction [PDF]

European Journal of Human Genetics, 2005
A recent study by McClung's group (2005),1 expanding on an earlier report,2 provides mechanistic insight to the timekeeper gene, Clock, which may regulate dopaminergic transmission and cocaine reward. This work provides further evidence that cocaine-induced effects have circadian influences.
Vadim Yuferov, Eduardo R Butelman, Mary J Kreek   +2 more
openaire   +1 more source

Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2011
Circadian clocks—ubiquitous in life forms ranging from bacteria to multicellular organisms—often exhibit intrinsic temperature compensation; the period of circadian oscillators is maintained constant over a range of physiological temperatures, despite ...
Tetsuhiro S. Hatakeyama, K. Kaneko
semanticscholar   +1 more source

Distributed quantum sensing in a continuous variable entangled network

, 2019
Networking plays a ubiquitous role in quantum technology. It is an integral part of quantum communication and has significant potential for upscaling quantum computer technologies that are otherwise not scalable. Recently, it was realized that sensing of
Andersen, Ulrik L., Borregaard, Johannes, Breum, Casper R., Christandl, Matthias, Gehring, Tobias, Guo, Xueshi, Izumi, Shuro, Larsen, Mikkel V., Neergaard-Nielsen, Jonas S.   +8 more
core   +1 more source

Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions [PDF]

, 2015
A workshop was held at the National Institute for Diabetes and Digestive and Kidney Diseases with a focus on the impact of sleep and circadian disruption on energy balance and diabetes.
Arble, Deanna M, Bass, Joseph, Behn, Cecilia Diniz, Butler, Matthew P, Challet, Etienne, Czeisler, Charles, Depner, Christopher M, Elmquist, Joel, Franken, Paul, Grandner, Michael A, Hanlon, Erin C, Joyner, Michael J, Karatsoreos, Ilia, Keene, Alex C, Kern, Philip A, Klein, Samuel, Morris, Christopher J, Pack, Allan I, Panda, Satchidananda, Ptacek, Louis J, Punjabi, Naresh M, Sassone-Corsi, Paolo, Saxena, Richa, Scheer, Frank A, Scheer, Frank A, Seaquest, Elizabeth R, Thimgan, Matthew S, Van Cauter, Eve, Wright, Kenneth P   +28 more
core   +4 more sources

Loss of functional cryptochrome 1 reduces robustness of 24-hour behavioral rhythms in monarch butterflies

iScience
Summary: Light is one of the strongest cues for entrainment of circadian clocks. While some insect species rely only on visual input, others like Drosophila melanogaster use both the visual system and the deep-brain blue-light photoreceptor cryptochrome ...
Samantha E. Iiams, Guijun Wan, Jiwei Zhang, Aldrin B. Lugena, Ying Zhang, Ashley N. Hayden, Christine Merlin   +6 more
doaj   +1 more source

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Farjo, Bessam, Farjo, Nilofer, Hardman, Jonathan A., Haslam, Iain S., Paus, Ralf   +4 more
core   +4 more sources

DNA methylation clocks for estimating biological age in Chinese cohorts

Protein & Cell
Epigenetic clocks are accurate predictors of human chronological age based on the analysis of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison between DNA methylation data and other omics datasets has not yet been performed.
Zikai Zheng, Jiaming Li, Tianzi Liu, Yanling Fan, Qiaocheng Zhai, M. Xiong, Qiaoran Wang, Xiaoyan Sun, Qiwen Zheng, Shanshan Che, Beier Jiang, Quan Zheng, Cui Wang, Lixiao Liu, Jiale Ping, Si Wang, Dan-dan Gao, Jinlin Ye, Kuan Yang, Yuesheng Zuo, Shuai Ma, Yungui Yang, J. Qu, Feng Zhang, Peilin Jia, Guanghui Liu, Weiqi Zhang   +26 more
semanticscholar   +1 more source

Dynamical fluctuations in biochemical reactions and cycles [PDF]

, 2010
We develop theory for the dynamics and fluctuations in some cyclic and linear biochemical reactions. We use the approach of maximum caliber, which computes the ensemble of paths taken by the system, given a few experimental observables. This approach may
Dill, K. A., Ghosh, K., Phillips, R., Pressé, S.   +3 more
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source