Results 81 to 90 of about 7,103,771 (354)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Machine learning-guided directed evolution for protein engineering [PDF]
, 2019 Machine learning (ML)-guided directed evolution is a new paradigm for biological design that enables optimization of complex functions. ML methods use data to predict how sequence maps to function without requiring a detailed model of the underlying ...
Arnold, Frances H. +2 more
core +1 more source
Exploring Comparative Physiology and Evolution: Understanding Homologous Structures with Students
Current: The Journal of Marine EducationA summer course designed for high school students compared different morphological features that evolved in response to locomotion. This course, as part of the USC Leslie and Bill McMorrow Neighborhood Academic Initiative (USC NAI), provided 20 students ...
Dieuwertje J. Kast +3 more
doaj +1 more source
Evolution: Education and Outreach, 2014 BackgroundIt is overwhelmingly acknowledged by the scientific community that evolution and global climate change (GCC) are undeniably supported by physical evidence. And yet, both topics remain politically contentious in the United States.
B. E. Carter, Jason R. Wiles
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Combining biological approaches to highlight the evolution of Musa complex [PDF]
, 2008 The diversity of the banana complex can be deciphered only by jointly characterizing the original wild species and their relatives, the primitive diploid forms and the triploid varieties.
Bakry, Frédéric +6 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The free energy requirements of biological organisms; implications for evolution
, 2016 Recent advances in nonequilibrium statistical physics have provided unprecedented insight into the thermodynamics of dynamic processes. The author recently used these advances to extend Landauer's semi-formal reasoning concerning the thermodynamics of ...
Wolpert, David H.
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Mass Extinctions vs. Uniformitarianism in Biological Evolution
, 1995 It is usually believed that Darwin's theory leads to a smooth gradual evolution, so that mass extinctions must be caused by external shocks. However, it has recently been argued that mass extinctions arise from the intrinsic dynamics of Darwinian ...
Bak, Per, Paczuski, Maya
core +3 more sources