Results 111 to 120 of about 4,841,906 (368)

Homogenization and influence of fragmentation in a biological invasion model

, 2009
In this paper, some properties of the minimal speeds of pulsating Fisher-KPP fronts in periodic environments are established. The limit of the speeds at the homogenization limit is proved rigorously.
Hamel, Francois, Roques, Lionel, Smaily, Mohammad El   +2 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Secondary metabolites in host pears defense against two fruit borers and cytochrome-P450-mediated counter-defense

iScience
Summary: Herbivorous insects have evolved metabolic strategies to survive the challenges posed by plant secondary metabolites (SMs). This study reports an exploration of SMs present in pears, which serve as a defense against invasive Cydia pomonella and ...
Shi-Pan Zhang, Bing Bai, Gao-Man Chen, Ya-Qi Wang, Chao Hu, Xu-Fei Liu, Ping Gao, Yu-Ting Li, Nan-Xia Fu, Xue-Qing Yang   +9 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Urban biological invasions

, 2023
MSc lecture on urban biological invasions for Technische Universität Berlin, Germany.
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Rapid and Portable Presumptive Loop‐Mediated Isothermal Amplification Assays for the Detection of the Invasive Corn Snake (Pantherophis guttatus)

Environmental DNA
The exotic pet trade is a major pathway for the introduction, establishment, and spread of novel invasive alien species. Reptiles are common in the exotic pet trade and are prominent invasive alien vertebrate species that have dire impacts if allowed to ...
Nathan Deliveyne, Jeremy J. Austin, Kate Sanders, Phillip Cassey   +3 more
doaj   +1 more source

Complexity and anisotropy in host morphology make populations safer against epidemic outbreaks

, 2010
One of the challenges in epidemiology is to account for the complex morphological structure of hosts such as plant roots, crop fields, farms, cells, animal habitats and social networks, when the transmission of infection occurs between contiguous hosts ...
Christopher A. Gilligan, Francisco J. Pérez-Reche, Franco M. Neri, Luciano da F. Costa, Murray J. D., Oztas E., Sergei N. Taraskin, Stauffer J.   +7 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Controlling the Biological Invasion of a Commercial Fishery by a Space Competitor: A Bioeconomic Model with Reference to the Bay of St-Brieuc Scallop Fishery [PDF]

This paper presents a bioeconomic model of a commercial fishery facing biological invasion by an alien species acting as a space competitor for the native species.
Boncoeur, Jean, Fresard, Marjolaine
core   +1 more source