Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source
Tree legumes: an underexploited resource in warm-climate silvopastures
Tree legumes are an underexploited resource in warm-climate silvopastures. Perceived benefits of tree legumes include provisioning (browse/mast, timber, fuel, human food, natural medicines, and ornamentals), regulating (C sequestration, greenhouse gas ...
José Carlos Batista Dubeux Junior +5 more
doaj +1 more source
Biological N2 fixation in the upwelling region off NW Iberia: magnitude, relevance and main players
Conference ...
Moreira-Coello, V. (Víctor) +6 more
openaire +2 more sources
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng +17 more
wiley +1 more source
Biomass production, symbiotic nitrogen fixation and inorganic N use in dual and tri-component annual intercrops [PDF]
The interspecific complementary and competitive interactions between pea (Pisum sativum L.), barley (Hordeum vulgare L.) and oilseed rape (Brassica napus L.), grown as dual and tri-component intercrops were assessed in a field study in Denmark.
Ambus, Per +3 more
core
To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...
Jieliang Zhao +12 more
wiley +1 more source
An experimental and modelling exploration of the host-sanction hypothesis in legume-rhizobia mutualism [PDF]
Despite the importance of mutualism as a key ecological process, its persistence in nature is difficult to explain since the existence of exploitative, 'cheating' partners that could erode the interaction is common. By analogy with the proposed
Angeles Hidalgo-Perea +7 more
core +1 more source
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Dual mutualistic associations in sainfoin (Onobrychis viciifolia Scop.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Agronomy at Massey University [PDF]
Recent studies established that many legumes, when infected with the appropriate Rhizobium spp. and arbuscular fungi, nodulated better and exhibited greater dinitrogen fixation than plants infected with only the rhizobia.
Kon, Kee Fui
core

