Results 121 to 130 of about 30,881 (256)

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

The model legume Medicago truncatula A17 is poorly matched for N2fixation with the sequenced microsymbiont Sinorhizobium meliloti 1021

, 2008
Medicago truncatula (barrel medic) A17 is currently being sequenced as a model legume, complementing the sequenced root nodule bacterial strain Sinorhizobium meliloti 1021 (Sm1021). In this study, the effectiveness of the Sm1021-M.
Terpolilli, J.J., Dilworth, M.J., Howieson, J.G., O'Hara, G.W., Tiwari, R.P.   +4 more
core  

Spatio-temporal variations of N2 fixation rates and abundance of N2-fixers in the north Western Pacific

, 2009
The availability of nitrogen is important in regulating biological productivity and deepwater nitrate has long been considered the major source of new nitrogen supporting primary production in oligotrophic regions of the open ocean.
E.J.Carpenter, 최동한, 노재훈
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Tree legumes: an underexploited resource in warm-climate silvopastures

Revista Brasileira de Zootecnia
Tree legumes are an underexploited resource in warm-climate silvopastures. Perceived benefits of tree legumes include provisioning (browse/mast, timber, fuel, human food, natural medicines, and ornamentals), regulating (C sequestration, greenhouse gas ...
José Carlos Batista Dubeux Junior, James P. Muir, Valéria Xavier de Oliveira Apolinário, P. K. Ramachandran Nair, Mario de Andrade Lira, Lynn E. Sollenberger   +5 more
doaj   +1 more source

Soybean yield, biological N₂ fixation and seed composition responses to additional inoculation in the United States. [PDF]

Sci Rep, 2019
Carciochi WD, Rosso LHM, Secchi MA, Torres AR, Naeve S, Casteel SN, Kovács P, Davidson D, Purcell LC, Archontoulis S, Ciampitti IA.   +10 more
europepmc   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

A Shipboard Instrument for Underway Estimates of Marine N2 Fixation

, 2016
Marine N2 fixation converts nitrogen gas into ammonia and accounts for the largest external nitrogen input to the oceans1. Since large portions of the global oceans are nitrogen deficient, marine N2 fixation can relieve the nitrogen limitation, thereby ...
Tang, Weiyi
core  

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Soil P availability limits legume persistence and distribution in the fynbos of the Cape Floristic Region

, 2010
Includes abstract.Includes bibliographical references (leaves 64-83).Legumes are unable to persist through post-fire succession in fynbos vegetation of the CFR unlike species in families such as Proteaceae and Restionaceae. The majority of fynbos legumes
Power, Simon C
core