FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
Combustion method for assay of biological materials labeled with carbon-14 or tritium, or double-labeled [PDF]
, 1969 Dry catalytic combustion at high temperatures is used for assaying biological materials labeled carbon-14 and tritium, or double-labeled. A modified oxygen-flask technique is combined with standard vacuum-line techniques and includes convenience of ...
Huebner, L. G., Kisieleski, W. E.
core +1 more source
Identification of putative steroid receptor antagonists in bottled water : combining bioassays and high-resolution mass spectrometry [PDF]
, 2013 Endocrine disrupting chemicals (EDCs) are man-made compounds interfering with hormone signaling and thereby adversely affecting human health. Recent reports provide evidence for the presence of EDCs in commercially available bottled water, including ...
Oehlmann, Jörg +3 more
core +3 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
INFLUENCE OF BIOLOGICAL PRODUCTS ON THE PRODUCTIVITY OF SUNFLOWER HYBRIDS
, 2023 The processes of growth, development and formation of seed productivity of sunflower hybrids depending on pre-sowing seed treatment with biological products. Subject of research. Sunflower plants, seeds, biological products. The experiments used zoned hybrids Darii, Yason, and Zorepad. Research results.
TRETIAKOVA, Svitlana, VITANOV, Evhen
openaire +1 more source
University Scholar Series: Brandon White [PDF]
, 2011 Use and Applications of HeLa Cells in Science and Biotechnology On October 26, 2011, Dr. Brandon White spoke in the University Scholar Series hosted by Provost Gerry Selter at the Dr. Martin Luther King, Jr. Library.
White, Brandon
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Follicle-Stimulating Hormone Biological Products: Does Potency Predict Clinical Efficacy? [PDF]
Int J Mol Sci, 2023 Lispi M +4 more
europepmc +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Initial prescriptions and medication switches of biological products: an analysis of prescription pathways and determinants in the Swiss healthcare setting. [PDF]
BMJ Open, 2023 Wirth K +4 more
europepmc +1 more source