Results 101 to 110 of about 3,684,448 (359)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Correction to: Comparing Serum Zinc and Cortisol Concentrations in Patients with Major Depressive Disorder Treated with Fluoxetine and Cognitive-Behavioral Therapy: A Randomized Clinical Trial [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Mehrdad Jalalian1, Mehdi Pourasghar2, Ahmad Majd3, Hossein Ghalehnoei4, Zahra Kianmehr5 1 PhD Student in Biochemistry, Department of Biochemistry, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, Iran 2 Associate
Mehrdad Jalalian, Mehdi Pourasghar, Ahmad Majd, Hossein Ghalehnoei, Zahra Kianmehr   +4 more
doaj  

Developmental imaging genetics: challenges and promises for translational research [PDF]

, 2006
Advances in molecular biology, neuroimaging, genetic epidemiology, and developmental psychopathology have provided a unique opportunity to explore the interplay of genes, brain, and behavior within a translational research framework.
Hariri, A.R., Viding, E., Williamson, D.E.   +2 more
core   +1 more source

Machine learning, statistical learning and the future of biological research in psychiatry

Psychological Medicine, 2016
Psychiatric research has entered the age of ‘Big Data’. Datasets now routinely involve thousands of heterogeneous variables, including clinical, neuroimaging, genomic, proteomic, transcriptomic and other ‘omic’ measures. The analysis of these datasets is
R. Iniesta, D. Ståhl, P. McGuffin
semanticscholar   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Abstracts of the 6th SFCNS Congress—Swiss Federation of Clinical Neuro-Societies Lausanne, Switzerland, 29–31 October 2025—United for Brain Health

Clinical and Translational Neuroscience
On behalf of the SFCNS, Swiss Federation of Clinical Neuro-Societies, we are pleased to present the Abstracts of the 6th SFCNS Congress, which will be held in Lausanne, Switzerland, 29–31 October 2025.
Swiss Federation of Clinical Neuro-Societies (SFCNS)
doaj   +1 more source

Addressing neuroticism in psychological treatment [PDF]

, 2017
Neuroticism has long been associated with psychopathology and there is increasing evidence that this trait represents a shared vulnerability responsible for the development and maintenance of a range of common mental disorders. Given that neuroticism may
Barlow, David H., Sauer-Zavala, Shannon, Wilner, Julianne G.   +2 more
core   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Psychiatry outside the framework of empiricism

Nigerian Postgraduate Medical Journal, 2017
Science is interested in whatever that is empirical and objective. Any claim that cannot be objectively demonstrated has no place in science, because the subject does not deviate from the role, which it has set out to play in the life of mankind ...
Celestine Okorome Mume
doaj   +1 more source

Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]

, 2010
We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core   +1 more source