Results 111 to 120 of about 3,265,963 (321)

Challenges and Future Prospects of Precision Medicine in Psychiatry

Pharmacogenomics and Personalized Medicine, 2020
Mirko Manchia,1– 3,* Claudia Pisanu,4,* Alessio Squassina,4,5 Bernardo Carpiniello1,2 1Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 2Unit of Clinical Psychiatry, University ...
Manchia M, Pisanu C, Squassina A, Carpiniello B   +3 more
doaj  

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

The stalwart – Adolf Meyer

Telangana Journal of Psychiatry
Adolf Meyer (1866–1950), a Swiss-born American psychiatrist, was a prominent figure in the development of Anglo-American psychiatry. He rose to prominence as the president of the American Psychiatric Association.
Ananya Makkena
doaj   +1 more source

Community psychiatry – Transcontinental lessons of the last quarter century

Indian Journal of Social Psychiatry, 2018
Fueled by the discovery of effective medications and the debilitative effects of psychiatric institutionalization and driven by the social winds of change, community psychiatry took shape all over the world. The gradual closure of asylums and the move to
T Manoj Kumar
doaj   +1 more source

Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice

Advanced Science, EarlyView.
An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen, Ruiqing Hou, Zhinan Chen, Junli Lu, Si Chen, Shisheng Xiong, Jianfeng Feng, Trevor W. Robbins, Haitao Yan, Xiao Xiao   +9 more
wiley   +1 more source

Biological Psychiatry in Displaced Populations: What We Know, and What We Need to Begin to Learn. [PDF]

Biol Psychiatry Cogn Neurosci Neuroimaging, 2022
Javanbakht A, Grasser LR.
europepmc   +1 more source

Biological Psychiatry and Reductionism Empirical Findings and Philosophy [PDF]

, 1995
Hasse Karlsson, Matti Kamppinen
openalex   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

Shaping tomorrow: how the STEP training course pioneered noninvasive brain stimulation training for psychiatry in France

Frontiers in Psychiatry
Over the past three decades, non-invasive brain stimulation (NIBS) techniques have gained worldwide attention and demonstrated therapeutic potential in various medical fields, particularly psychiatry. The emergence of these novel techniques has led to an
Marine Mondino, Marine Mondino, Marine Mondino, Cécilia Neige, Cécilia Neige, Cécilia Neige, Jean-Marie Batail, Jean-Marie Batail, Jean-Marie Batail, Jean-Marie Batail, Noomane Bouaziz, Noomane Bouaziz, Noomane Bouaziz, Noomane Bouaziz, Maxime Bubrovszky, Maxime Bubrovszky, Samuel Bulteau, Samuel Bulteau, Anastasia Demina, Anastasia Demina, Ludovic C. Dormegny-Jeanjean, Ludovic C. Dormegny-Jeanjean, Ludovic C. Dormegny-Jeanjean, Ghina Harika-Germaneau, Ghina Harika-Germaneau, Ghina Harika-Germaneau, Dominique Januel, Dominique Januel, Charles Laidi, Charles Laidi, Charles Laidi, Virginie Moulier, Virginie Moulier, Virginie Moulier, Marion Plaze, Marion Plaze, Arnaud Pouchon, Arnaud Pouchon, Emmanuel Poulet, Emmanuel Poulet, Emmanuel Poulet, Maud Rothärmel, Maud Rothärmel, Anne Sauvaget, Anne Sauvaget, Antoine Yrondi, Antoine Yrondi, Antoine Yrondi, David Szekely, David Szekely, Jerome Brunelin, Jerome Brunelin, Jerome Brunelin   +52 more
doaj   +1 more source