Results 1 to 10 of about 1,871,491 (306)
Late Breaking Biological Sciences Session [PDF]
Innov Aging, 2023 Blanka Rogina
europepmc +3 more sources
THIS IS THE YEAR THAT WAS: THE BEST OF THE JOURNAL OF GERONTOLOGY BIOLOGICAL SCIENCES [PDF]
Innov Aging, 2023 Gustavo Duque
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iScience, 2022 Summary: Aortic endothelial cell dysfunction is an early trigger of atherosclerosis, the major cause of the cardiovascular disease (CVD). Nanomedicines targeting vascular endothelium and lesions hold great promise as therapeutic solutions to vascular ...
Yuxiang Zhou +9 more
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Influence of data sampling methods on the representation of neural spiking activity in vivo
iScience, 2022 Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden +2 more
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The RBPMSCreERT2-tdTomato mouse line for studying retinal and vascular relevant diseases
iScience, 2023 Summary: RNA-binding protein with multiple splicing (RBPMS) plays a crucial role in cardiac mesoderm specification and cardiovascular development, as well as being a typical marker for whole retinal ganglion cells (RGCs).
Guilan Li +6 more
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Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
iScience, 2021 Summary: Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of the
Niklas Handin +10 more
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Top-down reconfiguration of SMA cortical connectivity during action preparation
iScience, 2023 Summary: The Bereitschaftspotential (BP), a scalp potential recorded in humans during action preparation, is characterized by a slow amplitude increase over fronto-central regions as action execution approaches.
Valentina Bianco +4 more
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Whole-brain optical access in a small adult vertebrate with two- and three-photon microscopy
iScience, 2022 Summary: Although optical microscopy has allowed scientists to study the entire brain in early developmental stages, access to the brains of live, adult vertebrates has been limited.
Najva Akbari +5 more
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iScience, 2023 Summary: Coordinated temporal control of gene expression is essential for physiological homeostasis, especially during metabolic transitions. However, the interplay between chromatin architectural proteins and metabolism in regulating transcription is ...
Devashish Sen +10 more
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The Rigor and Transparency Index Quality Metric for Assessing Biological and Medical Science Methods
iScience, 2020 Summary: The reproducibility crisis is a multifaceted problem involving ingrained practices within the scientific community. Fortunately, some causes are addressed by the author's adherence to rigor and reproducibility criteria, implemented via ...
Joe Menke +4 more
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