Results 31 to 40 of about 4,077,509 (297)
Beyond the null: Recognizing and reporting true negative findings
iScienceSummary: Science is based on ideas that might be true or false in describing reality. In order to discern between these two, scientists conduct studies that can reveal evidence for an idea, i.e., positive findings, or not, i.e., negative or null findings.
Manon K. Schweinfurth +1 more
doaj +1 more source
Tivantinib alleviates inflammatory diseases by directly targeting NLRP3
iScience, 2023 Summary: NLRP3 inflammasome-mediated immune responses are involved in the pathogenesis of multiple inflammatory diseases, but few clinical drugs are identified that directly target the NLRP3 inflammasome to treat these diseases to date.
Yi Huang +6 more
doaj +1 more source
VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels [PDF]
, 2017 We thank Vann Bennett and Daizing Zhou (Department of Biochemistry, Duke University Medical Center) for the design and generation of the Brn3bCre knock-in mice.
Bruce, Freyja +7 more
core +2 more sources
Little information loss with red-green color deficient vision in natural environments
iScience, 2023 Summary: Inherited color vision deficiency affects red-green discrimination in about one in twelve men from European populations. Its effects have been studied mainly in primitive foraging but also in detecting blushing and breaking camouflage. Yet there
David H. Foster, Sérgio M.C. Nascimento
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
iScienceSummary: The combination of vessel-labeling, tissue-clearing, and light-sheet imaging techniques provides a potent tool for accurately mapping vascular networks, enabling the assessment of vascular remodeling in vascular-related disorders.
Yating Deng +5 more
doaj +1 more source
iScience, 2022 Summary: Arthritic diseases have attracted enormous scientific interest because of increased worldwide prevalence and represent a significant socioeconomic burden. Osteoarthritis (OA) is the most prevalent form of arthritis.
Sergio Ramirez-Perez +4 more
doaj +1 more source
Scientific evaluation of deterioration of historic huts of Ross Island, Antarctica [PDF]
, 2007 There are many challenges facing conservation of the historic huts in Antarctica including non-biological, biological and environmental impacts explains Professor Roberta L. Farrell, Department of Biological Sciences, the University of Waikato.
Farrell, Roberta L.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source