Results 51 to 60 of about 2,170,303 (306)

Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant

iScience, 2022
Summary: Epilepsy and neurodevelopmental disorders can arise from pathogenic variants of KCNQ (Kv7) channels. A patient with developmental and epileptic encephalopathy exhibited an in-frame deletion of histidine 260 on Kv7.2. Coexpression of Kv7.2 mutant
Xiaoqin Zhan, Chris Drummond-Main, Dylan Greening, Jinjing Yao, S.W.R. Chen, J.P. Appendino, P. Y. Billie Au, Ray W. Turner   +7 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Biological Sciences Newsletter, Fall 2006 [PDF]

, 2006
This is the alumni newsletter for the Dept.

core  

Beta-cell-specific C3 deficiency exacerbates metabolic dysregulation and insulin resistance in obesity

Molecular Metabolism
Background: C3 is highly expressed in human and rodent pancreatic islets, which secrete insulin to regulate blood glucose homeostasis. We have previously shown that cytosolic C3 protects pancreatic beta-cells from stress, by allowing cytoprotective ...
Ben C. King, Lucie Colineau, Julia Slaby, Olga Kolodziej, Vaishnavi Dandavate, Robin Olsson, Malin Fex, Anna M. Blom   +7 more
doaj   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

Biological Sciences Newsletter, Spring 2006 [PDF]

, 2006
This is the alumni newsletter for the Dept.

core  

School of Biological Sciences News, 2020-2021 [PDF]

, 2020
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1006/thumbnail ...
School of Biological Sciences
core   +1 more source

Daily nocturnal homing reveals goal-directed navigation in a wild teleost

iScience
Summary: Understanding how free-ranging animals navigate large, low-visibility environments remains an important challenge in movement ecology. Using high-resolution acoustic telemetry, we investigated the movement behavior of adult pikeperch (Sander ...
Milan Říha, Ruben Rabaneda-Bueno, Ivan Jarić, Marie Prchalová, Petr Blabolil, Marek Šmejkal, Tomáš Jůza, Michal Tušer, Jan Kubečka, Jiří Peterka   +9 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Biological Sciences Newsletter, Winter 2011 [PDF]

, 2011
This is the alumni newsletter for the Dept.

core