Results 61 to 70 of about 4,077,509 (297)

Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]

, 2017
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu, Król, Elżbieta, Li, Baoguo, Li, Li, Li, Min, Li, Ting, Niu, Chaoqun, Speakman, John R., Wang, Guanlin   +8 more
core   +2 more sources

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Beta-cell-specific C3 deficiency exacerbates metabolic dysregulation and insulin resistance in obesity

Molecular Metabolism
Background: C3 is highly expressed in human and rodent pancreatic islets, which secrete insulin to regulate blood glucose homeostasis. We have previously shown that cytosolic C3 protects pancreatic beta-cells from stress, by allowing cytoprotective ...
Ben C. King, Lucie Colineau, Julia Slaby, Olga Kolodziej, Vaishnavi Dandavate, Robin Olsson, Malin Fex, Anna M. Blom   +7 more
doaj   +1 more source

Deterministic chaos theory and forecasting in Social Sciences. Contribution to the discussion [PDF]

, 2018
Forecasting social phenomena may be hampered in many ways. This is because in nature of these phenomena lies strong and multilateral connection with other social phenomena; but not only – also physical and biological (natural) ones.
Donaj, Łukasz
core   +2 more sources

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

A ZNF-nanobody fusion reveals SUMOylation-dependent changes in p53 protein localization

iScience
Summary: SUMOylation is a post-translational modification regulating protein localization, stability, and activity, with effects varying depending on the conjugated SUMO protein and type of SUMOylation.
Antoine Y. Bouchard, Valérie C. Cabana, Julien Plamondon, Chongyang Li, Anaïs J.I. Vivet, Sylvie Mader, Pierre Thibault, Marc P. Lussier, Laurent Cappadocia   +8 more
doaj   +1 more source

An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly [PDF]

, 2017
ACKNOWLEDGEMENTS Some strains were provided by the CGC, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). We would also like to thank Prof.
Albrecht, Allen, Barbee, Bell, Bernadette Connolly, Berndt Müller, Blumenthal, Blumenthal, Brahms, Brahms, Brenner, Bruzik, Conrad, Denker, Denker, Evans, Evans, Evans, Ferguson, Friesen, Fr⊘kjær-Jensen, George C. Pandarakalam, Godfrey, Hannon, Jonathan Pettitt, Jones, Kamath, Kamath, Kutscher, Lasda, Lasda, Li, Lucas Philippe, MacMorris, Maroney, Meister, Neale Harrison, Paushkin, Pellizzoni, Pettitt, Pettitt, Pillai, Pillai, Reuter, Rotimi Fasimoye, Ruegger, Schmittgen, Schneider, Sonnichsen, Stiernagle, Thomas, Timmons, Van Doren, Van Doren, Whitelaw   +54 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Cadmium disrupts hepatic lipid homeostasis: molecular mechanisms, unresolved controversies, and therapeutic strategies

iScience
Summary: Cadmium, a pervasive environmental toxicant with profound bioaccumulation potential, poses a significant threat to hepatic lipid homeostasis. This review systematically delineates the intricate molecular mechanisms underlying the cadmium-induced
Ruilong Li, Xuemeng Wang, Wanwan Liu, Mingjie Song, Tao Zeng, Cuili Zhang   +5 more
doaj   +1 more source