Results 41 to 50 of about 4,077,509 (297)

Compartment-specific antibody correlates of protection to SARS-CoV-2 Omicron in macaques

iScience
Summary: Antibodies represent a primary mediator of protection against respiratory viruses. Serum neutralizing antibodies (NAbs) are often considered a primary correlate of protection.
Xin Tong, Qixin Wang, Wonyeong Jung, Taras M. Chicz, Ross Blanc, Lily J. Parker, Dan H. Barouch, Ryan P. McNamara   +7 more
doaj   +1 more source

Race in the Life Sciences: An Empirical Assessment, 1950-2000 [PDF]

, 2015
The mainstream narrative regarding the evolution of race as an idea in the scientific community is that biological understandings of race dominated throughout the nineteenth and twentieth centuries up until World War II, after which a social ...
Darling, Katherine, Harris-Wai, Julie N., Keagy, Carolyn, Obasogie, Osagie K.   +3 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant

iScience, 2022
Summary: Epilepsy and neurodevelopmental disorders can arise from pathogenic variants of KCNQ (Kv7) channels. A patient with developmental and epileptic encephalopathy exhibited an in-frame deletion of histidine 260 on Kv7.2. Coexpression of Kv7.2 mutant
Xiaoqin Zhan, Chris Drummond-Main, Dylan Greening, Jinjing Yao, S.W.R. Chen, J.P. Appendino, P. Y. Billie Au, Ray W. Turner   +7 more
doaj   +1 more source

The effects of graded levels of calorie restriction : I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse [PDF]

, 2015
We acknowledge the BSU staff for their invaluable help with caring for the animals and anonymous referees for their inputs. The work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) of the UK (Standard grant BB/G009953 ...
Aspden, Richard M, Bruel, Aurélie, Chen, Luonan, Delville, Camille, Derous, Davina, Douglas, Alex, Goodyear, Simon R, Green, Cara, Han, Jackie J D, Kerbois, Celine, Konstantopedos, Penelope, Lusseau, David, Mitchell, Sharon E, Promislow, Daniel E L, Speakman, John R, Tang, Zhanhui, Wang, Yingchun   +16 more
core   +2 more sources

Peeling back the layers of coral holobiont multi-omics data

iScience, 2023
Summary: The integration of multiple ‘omics’ datasets is a promising avenue for answering many important and challenging questions in biology, particularly those relating to complex ecological systems.
Amanda Williams, Timothy G. Stephens, Alexander Shumaker, Debashish Bhattacharya   +3 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Psychology [PDF]

, 2014
Genetics and the biological sciences are the two contemporary scientific fields most readily called to mind in thinking about science and eugenics. Yet the history of another discipline, psychology, is enmeshed more intricately with eugenics than are the
Wilson, Robert A.
core  

New directions for the treatment of adrenal insufficiency [PDF]

, 2015
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen, Allende, Badylak, Bancos, Berkes, Birke, Buaas, Chamoux, Chamoux, Clipsham, Cogger, Cox, Crawford, Drucker, Dubernard, El-Khairi, Else, Faulk, Fayard, Franksson, Freedman, Gallo-Payet, Gondo, Gondo, Grodstein, Guasti, Guasti, Hardy, Hardy, Hardy, Hardy, Hatano, Huang, Huang, Ibbertson, Jadhav, Kearns, Kim, King, Laufer, Ludwig, Luo, Mazilu, Parker, Sancho-Martinez, Schimmer, Schnabel, Sonoyama, Takahashi, Tanaka, Teebken, Thomas, Thomas, Thomas, Thomas, Thomas, Val, Val, Vierbuchen, Vouillarmet, Walczak, Walczak, Wei, Wilhelm, Wong, Yazawa, Yazawa, Yazawa, Yazawa, Zupekan   +69 more
core   +2 more sources

Unifying the essential concepts of biological networks: biological insights and philosophical foundations [PDF]

, 2020
Over the last decades, network-based approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics.
Hilgetag, Claus, Kostic, Daniel, Tittgemeyer, Marc   +2 more
core   +2 more sources