Results 101 to 110 of about 1,871,491 (306)

Intrinsically robust and scalable biofilm segmentation under diverse physical growth conditions

iScience
Summary: Developmental patterning is a shared feature across biological systems ranging from vertebrates to bacterial biofilms. While vertebrate patterning benefits from well-controlled homeostatic environments, bacterial biofilms can grow in diverse ...
Jian-geng Chiou, Todd Kwang-Tao Chou, Jordi Garcia-Ojalvo, Gürol M. Süel   +3 more
doaj   +1 more source

Confronting historical legacies of biological anthropology in South Africa—Restitution, redress and community-centered science: The Sutherland Nine

, 2023
Victoria E. Gibbon, Loretta Feris, Joscha Gretzinger, Kathryn Smith, Simon Hall, Nigel Penn, Tinashe Mutsvangwa, Michaela Heale, Devin A. Finaughty, Yvonne Wanjiku Karanja, Jan Esterhuyse, Daniël Kotze, Nina Barnes, Geney Gunston, Je’nine May, Johannes Krause, Caroline Wilkinson, Stephan Schiffels, Doreen Februarie, Sianne Alves, Judith Sealy   +20 more
openalex   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

3-Deazaguanosine inhibits SARS-CoV-2 viral replication and reduces the risk of COVID-19 pneumonia in hamster

iScience
Summary: The COVID-19 pandemic highlighted the serious threat that coronaviruses have on public health. Because coronavirus continuously undergoes cross-species transmission, additional therapeutic agents and targets are urgently needed.
Noriko Saito-Tarashima, Takaaki Koma, Naoto Hinotani, Keigo Yoshida, Moka Ogasa, Akiho Murai, Syuya Inoue, Tomoyuki Kondo, Naoya Doi, Koichi Tsuneyama, Masako Nomaguchi, Noriaki Minakawa   +11 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Biological sciences: Promoting plants [PDF]

, 1974
H. J. Smith
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Spatial distribution of biological and physical sediment parameters in the western Gulf of Gdańsk**This project was funded by the Ministry of Science and Higher Education through a supervisor research grant, project No. N304 031 32/1614.

, 2013
Katarzyna Huzarska
openalex   +1 more source

National Academy of Sciences. 1975. Productivity of world ecosystems. Proc. Symp. 5th General Assembly of the Special Committee for the International Biological Program, 31 August‐1 September 1972, Seattle, Washington. NAS‐NRC, Washington, D.C. vii + 166 p. $11.50. [PDF]

, 1976
H. B. N. Hynes
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source