Results 111 to 120 of about 2,170,303 (306)

American Institute of Biological Sciences [PDF]

open access: yes, 2005
An important organization for biologists and science educators, the American Institute of Biological Sciences (AIBS) "was established as a national umbrella organization for the biological sciences in 1947 by 11 scientific societies as part of the ...

core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A two-component cocktail of engineered DIII nanoparticles elicits broadly neutralizing antibody responses against dengue virus in mice

open access: yesiScience
Summary: Dengue virus (DENV) is a mosquito-transmitted flavivirus; there are four serotypes (DENV1-4) that co-circulate globally. Primary infection causes self-limiting febrile illness, but secondary infection by a heterologous serotype can predispose to
Margarette C. Mariano   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Regulation of addiction by the insular cortex: The interplay between interoception and cognitive function

open access: yesiScience
Summary: The insular cortex (IC) functions as a pivotal core for interoception. Functional magnetic resonance imaging reveals how the IC integrates internal and external stimuli by observing its neural activation patterns.
Dan Tao   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Satellite-based forest structure metrics as a predictive tool for biodiversity in hyperdiverse tropical forests: A test of the habitat heterogeneity hypothesis in the tropics

open access: yesEnvironmental and Sustainability Indicators
Tropical forests hold the most species yet face the greatest threats and knowledge gaps. To improve tropical biodiversity knowledge we combined satellite-based LiDAR with in situ bird, mammal, and acoustic soundscape data, via camera and audio recorders,
David Luther   +12 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

4th Annual Biological Sciences Symposium, April 13, 2011 [PDF]

open access: yes, 2011
Undergraduate and graduate student research, Department of Biological ...
Department of Biological Sciences, Seton Hall University
core   +1 more source

Commensal human gut microbes produce species specific neuroactive compounds

open access: yesiScience
Summary: The gut microbiota communicates with multiple organs through neuroactive molecules, but the specific compounds produced remain unclear. We investigated eight commensal gut species, Lactococcus lactis, Enterococcus faecalis, Blautia producta ...
Anna M. Tingler   +12 more
doaj   +1 more source

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