Summary: We developed a workflow using multi-scale and multi-disciplinary experimental and computational approaches to analyze C-looping (the first phase of cardiac looping) of the chick across four developing hearts. We provide the first 3D datasets for
Nazanin Ebrahimi+5 more
doaj +1 more source
We take the potentialities that are studied in the biological sciences (e.g., totipotency) to be an important subtype of biological dispositions. The goal of this paper is twofold: first, we want to provide a detailed understanding of what biological ...
A Bird+37 more
core +1 more source
Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface
Summary: Although the immunological complexity of the maternal-fetal interface is well appreciated, the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently understood. To comprehend the composition and spatial orientation
Juliette Krop+18 more
doaj +1 more source
A Framework for Improving the Quality of Research in the Biological Sciences. [PDF]
The American Academy of Microbiology convened a colloquium to discuss problems in the biological sciences, with emphasis on identifying mechanisms to improve the quality of research.
Casadevall A+4 more
europepmc +2 more sources
Systems biology in animal sciences [PDF]
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A.+4 more
core +3 more sources
Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators [PDF]
This Letter was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Scottish Universities Life Sciences Alliance (SULSA) in 2011Peer ...
Abdelrahman, Mostafa Hamed+4 more
core +1 more source
Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates [PDF]
BB/H012494/1/ Biotechnology and Biological Sciences Research ...
Barg E+10 more
core +3 more sources
Integrating machine learning and multiscale modeling—perspectives, challenges, and opportunities in the biological, biomedical, and behavioral sciences [PDF]
Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret these data to ...
M. Alber+10 more
semanticscholar +1 more source
Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans
Summary: Azoospermia is a significant cause of male infertility, with non-obstructive azoospermia (NOA) being the most severe type of spermatogenic failure.
Junyan Liu+24 more
doaj +1 more source
Biophysical models accurately characterize the thermal energetics of a small invasive passerine bird
Summary: Effective management of invasive species requires accurate predictions of their invasion potential in different environments. By considering species’ physiological tolerances and requirements, biophysical mechanistic models can potentially ...
Marina Sentís+5 more
doaj +1 more source