iScienceSummary: Zebrafish and organoids, crucial for complex biological studies, necessitate an imaging system with deep tissue penetration, sample protection from environmental interference, and ample operational space.
Peng Deng +19 more
doaj
GwAAP: A genome-wide amino acid coding-decoding quantitative proteomics system
iScience, 2022 Summary: Mass spectrometry-based proteomic technology has greatly improved and has been widely applied in various biological science fields. However, proteome-wide accurate quantification of proteins in signaling pathways remains challenging.
Li Cheng +6 more
doaj
Biologically Inspired Nanomaterials: A Conference Report [PDF]
arXiv, 2007 The understanding of the nanoscale physical properties of biomolecules and biomaterials will ultimately promote the research in the biological sciences. In this review, we focused on theory, simulation, and experiments involving nanoscale materials inspired by biological systems.
arxiv
A Survey of Molecular Communication in Cell Biology: Establishing a New Hierarchy for Interdisciplinary Applications [PDF]
arXiv, 2020 Molecular communication (MC) engineering is inspired by the use of chemical signals as information carriers in cell biology. The biological nature of chemical signaling makes MC a promising methodology for interdisciplinary applications requiring communication between cells and other microscale devices.
arxiv
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Biological Computing Fundamentals and Futures [PDF]
arXiv, 2009 The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored to discuss the possibilities of a new computing paradigm.
arxiv
Cyclin-dependent kinases as drug targets for cell growth and proliferation disorders. A role for systems biology approach in drug development. Part II - CDKs as drug targets in hypertrophic cell growth. Modelling of drugs targeting CDKs [PDF]
, 2012 Cyclin-dependent kinases (CDKs) are key regulators of cell growth and proliferation. Impaired regulation of their activity leads to various diseases such as cancer and heart hypertrophy.
Idowu, Michael A.
core +2 more sources
Efficient sampling methodologies for lake littoral invertebrates in compliance with the European Water Framework Directive [PDF]
, 2015 Lake shores are characterised by a high natural variability, which is increasingly threatened by a multitude of anthropogenic disturbances including morphological alterations to the littoral zone. The European Water Framework Directive (EU WFD) calls for
Brauns, Mario +7 more
core +1 more source
Searching Data: A Review of Observational Data Retrieval Practices in Selected Disciplines [PDF]
, 2019 A cross-disciplinary examination of the user behaviours involved in seeking and evaluating data is surprisingly absent from the research data discussion. This review explores the data retrieval literature to identify commonalities in how users search for
Aloia N. +10 more
core +2 more sources
Cellular interactions in the tumor microenvironment: the role of secretome [PDF]
, 2019 Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix ...
Castelo-Branco, Pedro +6 more
core +1 more source