Results 11 to 20 of about 510,635 (307)
evoText: A new tool for analyzing the biological sciences [PDF]
We introduce here evoText, a new tool for automated analysis of the literature in the biological sciences. evoText contains a database of hundreds of thousands of journal articles and an array of analysis tools for generating quantitative data on the nature and history of life science, especially ecology and evolutionary biology. This article describes
Ramsey, Grant, Pence, Charles H.
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Systems biology in animal sciences [PDF]
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
H. Woelders +4 more
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Summary: Early detection of pathogenic bacteria is needed for rapid diagnostics allowing adequate and timely treatment of infections. In this study, we show that secondary electrospray ionization–high resolution mass spectrometry (SESI-HRMS) can be used ...
Alejandro Gómez-Mejia +7 more
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Summary: The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular matrix ...
Bernhard Illes +6 more
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Polyvalent guide RNAs for CRISPR antivirals
Summary: CRISPR effector Cas13 recognizes and degrades RNA molecules that are complementary to its guide RNA (gRNA) and possesses potential as an antiviral biotechnology because it can degrade viral mRNA and RNA genomes.
Rammyani Bagchi +6 more
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Summary: Functional explication of genes is of great scientific value. However, conventional methods have challenges for those genes that may affect biological processes but are not annotated in public databases.
Ying Wang +13 more
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Development of small fluorescent probes for the analysis of autophagy kinetics
Summary: Autophagy is a dynamic process that degrades subcellular constituents, and its activity is measured by autophagic flux. The tandem proteins RFP-GFP-LC3 and GFP-LC3-RFP-LC3ΔG, which enable the visualization of autophagic vacuoles of different ...
Hajime Tajima Sakurai +9 more
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Automated design of gene circuits with optimal mushroom-bifurcation behavior
Summary: Recent advances in synthetic biology are enabling exciting technologies, including the next generation of biosensors, the rational design of cell memory, modulated synthetic cell differentiation, and generic multifunctional biocircuits.
Irene Otero-Muras +3 more
doaj +1 more source
Mass spectrometry-based proteomics as a tool to identify biological matrices in forensic science [PDF]
In forensic casework analysis, identification of the biological matrix and the species of a forensic trace, preferably without loss of DNA, is of major importance. The biological matrices that can be encountered in a forensic context are blood (human or non-human), saliva, semen, vaginal fluid, and to a lesser extent nasal secretions, feces, and urine.
Van Steendam, Katleen +4 more
openaire +3 more sources
Development of animal models and molecular tools to investigate the function of prostate specific membrane antigen. [PDF]
Prostate Specific Membrane Antigen (PSMA) is a transmembrane glycoprotein expressed in human prostate luminal epithelial cells. PSMA expression increases in most prostate cancer cases.
Rege, Apurv
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