Results 61 to 70 of about 1,326,546 (323)
All-Optical Volumetric Physiology for Connectomics in Dense Neuronal Structures
iScience, 2019 Summary: All-optical physiology (AOP) manipulates and reports neuronal activities with light, allowing for interrogation of neuronal functional connections with high spatiotemporal resolution. However, contemporary high-speed AOP platforms are limited to
Chiao Huang +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small +3 more
wiley +1 more source
MALVA: Genotyping by Mapping-free ALlele Detection of Known VAriants
iScience, 2019 Summary: The amount of genetic variation discovered in human populations is growing rapidly leading to challenging computational tasks, such as variant calling.
Luca Denti +4 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2022 LC–MS/MS is a major analytical platform for metabolomics, which has become a recent hotspot in the research fields of life and environmental sciences. By contrast, structure elucidation of small molecules based on LC–MS/MS data remains a major challenge ...
Zhitao Tian +4 more
doaj +1 more source
A First Exposure to Statistical Mechanics for Life Scientists [PDF]
, 2007 Statistical mechanics is one of the most powerful and elegant tools in the quantitative sciences. One key virtue of statistical mechanics is that it is designed to examine large systems with many interacting degrees of freedom, providing a clue that it ...
Garcia, Hernan G. +4 more
core
Biological Systems from an Engineer’s Point of View [PDF]
, 2009 Mathematical modeling of the processes that pattern embryonic development (often called biological pattern formation) has a long and rich history [1,2].
Fraser, Scott E., Reeves, Gregory T.
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine +10 more
wiley +1 more source
Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET
iScience, 2018 Summary: The therapeutic action of a drug depends on its ability to engage with its molecular target in vivo. However, current drug discovery strategies quantify drug levels within organs rather than determining the binding of drugs directly to their ...
Diana C. Alcobia +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis +13 more
wiley +1 more source
Architectural Principles for Characterizing the Performance of Antithetic Integral Feedback Networks
iScience, 2019 Summary: As we begin to design increasingly complex synthetic biomolecular systems, it is essential to develop rational design methodologies that yield predictable circuit performance.
Noah Olsman +2 more
doaj +1 more source