Results 81 to 90 of about 1,974,684 (305)

Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors

Human Vaccines & Immunotherapeutics, 2017
The usual treatments for patients with non-small-cell lung cancer (NSCLC), such as advanced lung adenocarcinoma, are unspecific and aggressive, and include lung resection, radiotherapy and chemotherapy.
Ana P. S. Silva, Priscila V. Coelho, Maristella Anazetti, Patricia U. Simioni   +3 more
doaj   +1 more source

Bilateral Assessment of Functional Tasks for Robot-assisted Therapy Applications [PDF]

, 2011
This article presents a novel evaluation system along with methods to evaluate bilateral coordination of arm function on activities of daily living tasks before and after robot-assisted therapy. An affordable bilateral assessment system (BiAS) consisting
AC Lo, AR Fugl-Meyer, B Rohrer, B Steenbergen, C Wu, CG Burgar, DE Nathan, DG Kamper, DJ Serrien, DJ Wilson, Elaine Strachota, G Kwakkel, GN Lewis, Guennady Tchekanov, J Cauraugh, J Whitall, Jeff Melbye, JJ Craig, John McGuire, JRM Spencer, KC Stewart, KJ Wisneski, L Dipietro, LG Portney, MC Cirstea, MF Levin, Michelle J. Johnson, ML Harris-Love, MV Radomski, O Kazennikov, Ping Bai, PS Lum, PW Duncan, R Braddom, R Loureiro, Sarah Wang, SC Cramer, WS McCombe, WS McCombe, Y Hseih, YC Hung   +40 more
core   +2 more sources

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Radiological outcomes in perianal fistulizing Crohn's disease: A systematic review and meta‐analysis

JGH Open, 2020
Perianal fistulas are a common and debilitating manifestation of Crohn's disease. Since the advent of biological agents, patient outcomes appear to have improved.
Tanya Lee, Eric Yong, Nik S Ding
doaj   +1 more source

Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control

, 2019
We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy.
Abolfath, Ramin, Bronk, Lawrence, Carabe, Alejandro, Grosshans, David, Helo, Yusuf, Mohan, Radhe   +5 more
core   +1 more source

Early research on the biological effects of microwave radiation: 1940?1960 [PDF]

, 1980
Two overriding considerations shaped the development of early research on the biological effects of microwave radiation?possible medical application (diathermy) and uncertainty about the hazards of exposure to radar.
Cook, HJ, Kane, GL, Steneck, NH, Vander, AJ   +3 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

LONG-TERM RETENTION RATE OF CERTOLIZUMAB PEGOL IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: DATA FROM THE TURKBIO REGISTRY

Rheumatology Quarterly
Aim: Selecting the most effective treatment plan for a patient represents one of the most challenging issues in contemporary rheumatology. Clinicians must consider the long-term retention rate and the reasons for discontinuing candidate drugs.This study ...
Ahmet Karataş, Yavuz Pehlivan, Servet Akar, Soner Şenel, Aslıhan Avanoğlu Güler, Özgül Soysal Gündüz, Ayten Yazıcı, Sema Yılmaz, Rabia Pişkin Sağır, Nevsun İnanç, Gözde Yıldırım Çetin, Mehmet Pamir Atagündüz, Fatoş Önen   +12 more
doaj   +1 more source