Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Splitting probabilities of confined chiral active Brownian particles
Active particles exhibit self-propulsion, leading to transport behavior that differs fundamentally from passive Brownian motion. In confined or structured domains, activity strongly influence escape probabilities and first-passage behavior. Understanding
Sarafa A Iyaniwura, Zhiwei Peng
doaj +1 more source
Coupled Transport/Hyperelastic Model for High Energy Density Nastic Materials [PDF]
A new development in aerospace technology involves the creation of aircraft that can undergo large changes in the shape of their wings and control surfaces.
Homison, Christopher Joseph
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Insulated conducting cantilevered nanotips and two-chamber recording system for high resolution ion sensing AFM. [PDF]
Biological membranes contain ion channels, which are nanoscale pores allowing controlled ionic transport and mediating key biological functions underlying normal/abnormal living.
Arce, Fernando Teran +3 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Methodological advances in imaging intravital axonal transport [version 1; referees: 3 approved]
Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction.
James N. Sleigh +3 more
doaj +1 more source
Learning to control active matter
The study of active matter has revealed novel non-equilibrium collective behaviors, illustrating their potential as a new materials platform. However, most work treat active matter as unregulated systems with uniform microscopic energy input, which we ...
Martin J. Falk +3 more
doaj +1 more source
A numerical tool to integrate biophysical diversity of a large regulated river: hydrobiogeochemical bases. The case of the Garonne River (France) [PDF]
This article presents the bases of a hydrobiogeochemical model of the Garonne River (southwest France) which has been developed to integrate physical and biological processes during summer low-water periods. The physical part of this model is composed of
APHA +32 more
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

